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骨替代物和远皮质锁定技术在两部分近端肱骨骨折重建中的力学效应:一项尸体研究

Mechanical Effects of Bone Substitute and Far-Cortical Locking Techniques in 2-Part Proximal Humerus Fracture Reconstruction: A Cadaveric Study.

作者信息

Hast Michael W, Chin Matthew, Schmidt Elaine C, Sanville Jennifer, Van Osten George Karl, Mehta Samir

机构信息

Biedermann Lab for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA; and.

Department of Orthopaedic Surgery, North Mississippi Medical Center, Tupelo, MS.

出版信息

J Orthop Trauma. 2020 Apr;34(4):199-205. doi: 10.1097/BOT.0000000000001668.

Abstract

OBJECTIVES

To make direct comparisons of the biomechanical properties of a control (CTL) group and implants that were augmented with far cortical locking (FCL), bone substitute material (BSM), and a combination of both (ALL) to determine which fixation is most effective in reducing implant failure.

METHODS

The constructs were tested with osteopenic cadaveric specimens in a two-part fracture model. Specimens were subjected to a battery of nondestructive torsion and axial compression tests, followed by a cyclic test. Construct stiffness and cycles to failure were documented, pre- and post-test fluoroscopy was performed, and implant and bone kinematics were quantified.

RESULTS

During nondestructive testing, the BSM group exhibited significantly increased torsional and axial stiffness compared with the FCL (P = 0.006, P < 0.001) group and ALL group (P < 0.001, P = 0.006). There were no significant differences in resistance to cyclic loading between groups. Fluoroscopic analysis indicated significant differences in the motions of nonlocked cannulated screws (used in BSM and ALL) versus locked screws (used in CTL and FCL).

CONCLUSIONS

Patients with poor bone quality and proximal humerus fracture may necessitate added compliance or rigidity to achieve fixation. Both have exhibited favorable biomechanical characteristics in this cadaveric 2-part proximal humerus fracture model.

摘要

目的

对对照组(CTL)以及采用远皮质锁定(FCL)、骨替代材料(BSM)和两者联合应用(ALL)增强固定的植入物的生物力学性能进行直接比较,以确定哪种固定方式在减少植入物失败方面最有效。

方法

在骨质疏松的尸体标本上,采用两部分骨折模型对构建物进行测试。标本接受一系列无损扭转和轴向压缩试验,随后进行循环试验。记录构建物的刚度和失效循环次数,在试验前后进行荧光透视检查,并对植入物和骨骼的运动学进行量化。

结果

在无损测试期间,与FCL组(P = 0.006,P < 0.001)和ALL组(P < 0.001,P = 0.006)相比,BSM组的扭转刚度和轴向刚度显著增加。各组之间在抗循环加载方面无显著差异。荧光透视分析表明,非锁定空心螺钉(用于BSM和ALL)与锁定螺钉(用于CTL和FCL)的运动存在显著差异。

结论

骨质较差且患有肱骨近端骨折的患者可能需要增加顺应性或刚性以实现固定。在这个尸体两部分肱骨近端骨折模型中,两者均表现出良好的生物力学特性。

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