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健康婴儿 F 波的年龄相关性特征和正常值。

Age-related characteristics and normative values of F waves in healthy infants.

机构信息

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China.

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China.

出版信息

Clin Neurophysiol. 2020 May;131(5):1068-1074. doi: 10.1016/j.clinph.2020.02.013. Epub 2020 Mar 3.

DOI:10.1016/j.clinph.2020.02.013
PMID:32197129
Abstract

OBJECTIVE

To establish age-related characteristics and normative values of F waves in healthy Chinese infants.

METHODS

We studied median, ulnar and tibial nerves on one side distally in 229 healthy Chinese infants (108 males) ranging from 1 to 12 months old.

RESULTS

Minimal F-wave latencies (Fmin) showed a strong negative correlation to the age for median, ulnar and tibial nerves (P < 0.01) but no correlation to the height. Statistical analyses revealed a significant (P < 0.01) decrease of Fmin during the second month of life and no change (P > 0.05) thereafter. Dividing the infants into 1 month old (Group 1) and 2-12 months old (Group 2), normal values (Mean ± SD ms) of Fmin for tibial, median and ulnar nerves consisted of 23.38 ± 1.68, 17.19 ± 0.95 and 16.47 ± 1.06 for Group 1 and 21.42 ± 1.25, 14.50 ± 1.15 and 14.52 ± 0.90 for Group 2.

CONCLUSION

F-wave latencies shorten in the 2nd month of life and change little thereafter when age-related maturation counters the concomitant growth of the nerve length.

SIGNIFICANCE

F waves can assess infantile neuropathies as a reliable measure, complementing the technically difficult conventional nerve conduction study in short limbs.

摘要

目的

建立健康中国婴儿 F 波的年龄相关性特征和正常值。

方法

我们研究了 229 名健康中国婴儿(108 名男性)一侧的正中神经、尺神经和腓总神经,年龄从 1 至 12 个月。

结果

最小 F 波潜伏期(Fmin)与正中神经、尺神经和腓总神经的年龄呈强负相关(P<0.01),但与身高无关。统计学分析显示,Fmin 在生命的第二个月显著下降(P<0.01),此后无变化(P>0.05)。将婴儿分为 1 个月龄(第 1 组)和 2-12 个月龄(第 2 组),腓总神经、正中神经和尺神经的 Fmin 正常值(Mean±SD ms)分别为第 1 组 23.38±1.68、17.19±0.95 和 16.47±1.06,第 2 组 21.42±1.25、14.50±1.15 和 14.52±0.90。

结论

F 波潜伏期在生命的第二个月缩短,此后随着与年龄相关的成熟与神经长度的同时生长相抗衡,变化很小。

意义

F 波可以作为一种可靠的测量方法来评估婴儿神经病,补充了在短肢中技术上困难的常规神经传导研究。

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