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Intradialytic parenteral nutrition improves nutritional status in a complex cystic fibrosis patient with redo double lung transplant and end-stage renal disease.血液透析期间胃肠外营养改善了一名患有再次双肺移植和终末期肾病的复杂囊性纤维化患者的营养状况。
BMJ Case Rep. 2020 Mar 19;13(3):e233346. doi: 10.1136/bcr-2019-233346.
2
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J Ren Nutr. 1999 Oct;9(4):206-13. doi: 10.1016/s1051-2276(99)90036-5.
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Effect of intradialytic parenteral nutrition in patients with malnutrition-inflammation complex syndrome on body weight, inflammation, serum lipids and adipocytokines: results from a pilot study.透析期间肠外营养对营养不良-炎症复合综合征患者体重、炎症、血脂及脂肪细胞因子的影响:一项初步研究结果
Eur J Clin Nutr. 2008 Jun;62(6):789-95. doi: 10.1038/sj.ejcn.1602777. Epub 2007 May 16.
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The use of intradialytic parenteral nutrition to treat malnutrition: a case study.采用透析期间胃肠外营养治疗营养不良:一项病例研究。
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nPCR assessment and IDPN treatment of malnutrition in pediatric hemodialysis patients.儿科血液透析患者营养不良的nPCR评估及IDPN治疗
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本文引用的文献

1
Clinical practice guideline on undernutrition in chronic kidney disease.慢性肾脏病营养不良临床实践指南
BMC Nephrol. 2019 Oct 16;20(1):370. doi: 10.1186/s12882-019-1530-8.
2
The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-fifth adult lung and heart-lung transplant report-2018; Focus theme: Multiorgan Transplantation.国际心肺移植学会国际胸科器官移植登记处:2018年第35份成人肺和心肺移植报告;重点主题:多器官移植。
J Heart Lung Transplant. 2018 Oct;37(10):1169-1183. doi: 10.1016/j.healun.2018.07.020. Epub 2018 Aug 11.
3
Interdialytic Weight Gain: Trends, Predictors, and Associated Outcomes in the International Dialysis Outcomes and Practice Patterns Study (DOPPS).透析间期体重增加:国际透析结局和实践模式研究(DOPPS)中的趋势、预测因素和相关结局。
Am J Kidney Dis. 2017 Mar;69(3):367-379. doi: 10.1053/j.ajkd.2016.08.030. Epub 2016 Nov 17.
4
ESPEN-ESPGHAN-ECFS guidelines on nutrition care for infants, children, and adults with cystic fibrosis.欧洲临床营养与代谢学会(ESPEN)、欧洲儿科胃肠病学、肝病学和营养学会(ESPGHAN)以及欧洲囊性纤维化协会(ECFS)关于囊性纤维化婴儿、儿童和成人营养护理的指南。
Clin Nutr. 2016 Jun;35(3):557-77. doi: 10.1016/j.clnu.2016.03.004. Epub 2016 Mar 15.
5
Systematic review of evidence for the use of intradialytic parenteral nutrition in malnourished hemodialysis patients.系统评价血液透析患者营养不良时使用透析中肠外营养的证据。
J Ren Nutr. 2010 Jan;20(1):1-7. doi: 10.1053/j.jrn.2009.08.003. Epub 2009 Sep 27.
6
EBPG guideline on nutrition.欧洲最佳实践指南:营养
Nephrol Dial Transplant. 2007 May;22 Suppl 2:ii45-87. doi: 10.1093/ndt/gfm020.
7
The effect of sevelamer on the pharmacokinetics of cyclosporin A and mycophenolate mofetil after renal transplantation.司维拉姆对肾移植后环孢素A和霉酚酸酯药代动力学的影响。
Nephrol Dial Transplant. 2004 Oct;19(10):2630-3. doi: 10.1093/ndt/gfh446. Epub 2004 Aug 10.
8
Definition of standardized nutritional assessment and interventional pathways in oncology.肿瘤学中标准化营养评估及干预路径的定义
Nutrition. 1996 Jan;12(1 Suppl):S15-9. doi: 10.1016/0899-9007(96)90011-8.

血液透析期间胃肠外营养改善了一名患有再次双肺移植和终末期肾病的复杂囊性纤维化患者的营养状况。

Intradialytic parenteral nutrition improves nutritional status in a complex cystic fibrosis patient with redo double lung transplant and end-stage renal disease.

作者信息

Melville Tahlia, Vardy Katie, Milliner Lucy, Angus Rebecca

机构信息

Nutrition and Food Services, Gold Coast Hospital and Health Service, Southport, Queensland, Australia

Nutrition and Food Services, Gold Coast Hospital and Health Service, Southport, Queensland, Australia.

出版信息

BMJ Case Rep. 2020 Mar 19;13(3):e233346. doi: 10.1136/bcr-2019-233346.

DOI:10.1136/bcr-2019-233346
PMID:32198225
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7103805/
Abstract

This case study reports on the use of intradialytic parenteral nutrition (IDPN) to address severe malnutrition in a 38-year-old woman, redo double lung transplant recipient with a complex medical history including cystic fibrosis and end-stage renal disease (ESRD) on haemodialysis. Gastroparesis and severe postprandial abdominal pain limited oral/enteral nutrition input. The addition of IDPN resulted in a dry weight increase of 13.6% over a 12-month period and an improvement in the patient's malnutrition status from severe (Patient-Generated Subjective Global Assessment (PG SGA) C24) to moderate (PG SGA B7). The patient stated she would recommend IDPN to others in a similar situation. Management of patients with coexisting cystic fibrosis and ESRD with or without haemodialysis requires patient engagement in treatment planning and a multidisciplinary team approach for clinical judgement in the absence of guidelines. As advances in medical care see more patients with these coexisting conditions, IDPN may provide an increasingly useful adjunct therapy.

摘要

本病例研究报告了一位38岁女性再次进行双肺移植受者使用透析期间胃肠外营养(IDPN)治疗严重营养不良的情况。该患者有复杂的病史,包括囊性纤维化和终末期肾病(ESRD),正在接受血液透析。胃轻瘫和严重的餐后腹痛限制了口服/肠内营养的摄入。在12个月的时间里,添加IDPN使患者干重增加了13.6%,患者的营养不良状况从严重(患者主观整体评估(PG-SGA)C24)改善为中度(PG-SGA B7)。患者表示,她会向处于类似情况的其他人推荐IDPN。对于同时患有囊性纤维化和ESRD且接受或未接受血液透析的患者,在缺乏指南的情况下,治疗管理需要患者参与治疗计划,并采用多学科团队方法进行临床判断。随着医疗护理的进步,越来越多的患者患有这些并存疾病,IDPN可能会成为一种越来越有用的辅助治疗方法。