HIV 相关睡眠障碍的代谢组学：叙述性综述。
Metabolomics of sleep disorders in HIV: a narrative review.
机构信息
Nell Hodgson Woodruff School of Nursing, Emory University, 1520 Clifton Rd, Atlanta, GA, 30322, USA.
Rollins School of Public Health, Emory University, Atlanta, GA, USA.
出版信息
Sleep Breath. 2020 Dec;24(4):1333-1337. doi: 10.1007/s11325-019-01993-2. Epub 2020 Mar 20.
PURPOSE
Sleep disturbances are prevalent among patients with human immunodeficiency virus (HIV), even those who are being treated on antiretroviral therapy. It is important to understand the metabolomic mechanisms underlying sleep disturbances among people living with HIV (PLWH).
METHODS
A review of recent literature was performed to explore the use of metabolomics in understanding sleep among PLWH.
RESULTS
We found only two studies that used metabolomics to explore sleep health among PLWH.
CONCLUSION
This paper reviews common sleep disorders in HIV, the existing metabolomic studies that may explain the relationship, and implications for future research. The use of metabolomics in exploring sleep disorders among PLWH will help to elucidate mechanistic links to improve patient outcomes.
目的
睡眠障碍在感染人类免疫缺陷病毒 (HIV) 的患者中很常见，即使是那些正在接受抗逆转录病毒治疗的患者也是如此。了解人类免疫缺陷病毒感染者 (PLWH) 睡眠障碍的代谢组学机制非常重要。
方法
对近期文献进行了综述，以探讨代谢组学在理解 PLWH 睡眠中的应用。
结果
我们仅发现两项使用代谢组学研究 PLWH 睡眠健康的研究。
结论
本文综述了 HIV 常见的睡眠障碍、可能解释其相关性的现有代谢组学研究以及对未来研究的影响。代谢组学在探索 PLWH 睡眠障碍中的应用将有助于阐明改善患者预后的机制联系。
Zotero 插件