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腿部溃疡中自体皮片移植的成活情况:传统敷料与局部改良负压敷料的比较

Split Skin Graft Take in Leg Ulcers: Conventional Dressing Versus Locally Adapted Negative Pressure Dressing.

作者信息

Maduba Charles Chidiebele, Nnadozie Ugochukwu Uzodimma, Modekwe Victor Ifeanyichukwu, Onah Ifeanyichukwu Igwilo

机构信息

Department of Surgery, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria.

Department of Surgery, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria; Department of Surgery, Ebonyi State University, Abakaliki, Nigeria.

出版信息

J Surg Res. 2020 Jul;251:296-302. doi: 10.1016/j.jss.2020.01.029. Epub 2020 Mar 18.

Abstract

BACKGROUND

Split-thickness skin grafting is widely used in the management of leg ulcers but is fraught with suboptimal take especially in less than ideal wound beds. The use of negative pressure dressing to prepare wound beds is an established practice. However, its use to improve graft survival is yet to be a common practice. We aim to compare quantitative and qualitative split thickness skin graft take in leg and foot ulcers using either traditional wound dressing or negative pressure dressing methods.

METHODS

Sixty-two cases were recruited for the study and assigned into two groups of 31 cases each by convenient sampling method. Group A patients had negative pressure dressings in both phases, whereas group B patients had traditional wound dressing in both phases. The percentage skin graft take for both groups, and the pattern of complications were assessed. Results were analyzed using IBM SPSS statistics for windows (version 21.0; IBM Corp, Armonk, NY). Student t-test was used to compare the percentage graft take, whereas Chi-square was used to compare significance of complications in both dressing methods.

RESULTS

The negative pressure dressing showed better skin graft take with mean value of 99.2 ± 0.95% compared with traditional dressing with mean take of 89.7 ± 6.44%, which was statistically significant with a P value of <0.001. The complication rate was 12.9% in the negative pressure dressing group and 96.8% in the traditional wound dressing group, showing about 7.5 times more complication in the traditional wound dressing. This is statistically significant with a P value < 0.001.

CONCLUSIONS

Negative pressure dressing for split-thickness skin graft contributes significantly to improved split-thickness skin graft take with reduced complication rate as compared with conventional wound dressing method.

摘要

背景

分层皮片移植广泛应用于腿部溃疡的治疗,但移植成功率欠佳,尤其是在不理想的创面床情况下。使用负压敷料来准备创面床是一种既定的做法。然而,其用于提高移植皮片成活率尚未成为普遍做法。我们旨在比较使用传统伤口敷料或负压敷料方法时,腿部和足部溃疡分层皮片移植的定量和定性成功率。

方法

本研究招募了62例患者,采用便利抽样法将其分为两组,每组31例。A组患者在两个阶段均使用负压敷料,而B组患者在两个阶段均使用传统伤口敷料。评估两组的皮片移植成功率以及并发症模式。使用IBM SPSS for Windows统计软件(版本21.0;IBM公司,纽约州阿蒙克)对结果进行分析。采用学生t检验比较移植成功率百分比,而使用卡方检验比较两种敷料方法并发症的显著性。

结果

负压敷料显示出更好的皮片移植成功率,平均值为99.2±0.95%,而传统敷料的平均值为89.7±6.44%,差异具有统计学意义,P值<0.001。负压敷料组的并发症发生率为12.9%,传统伤口敷料组为96.8%,传统伤口敷料的并发症约为负压敷料的7.5倍。这具有统计学意义,P值<0.001。

结论

与传统伤口敷料方法相比,负压敷料用于分层皮片移植可显著提高分层皮片移植成功率并降低并发症发生率。

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