Hysteroscopy Center, Fu Xing Hospital, Capital Medical University, Beijing 100038, China.
Hysteroscopy Center, Fu Xing Hospital, Capital Medical University, Beijing 100038, China.
Reprod Biomed Online. 2020 Apr;40(4):539-546. doi: 10.1016/j.rbmo.2019.11.017. Epub 2019 Dec 10.
Does placing an intrauterine balloon for different durations (7, 14 or 28 days) affect the recurrence of intrauterine adhesions after hysteroscopic adhesiolysis?
Prospective randomized control trial involving 138 patients recruited over a 12-month period and followed up post-operatively for 15 months. The primary outcome measure was the rate of adhesion reformation at third-look hysteroscopy.
At third-look hysteroscopy, 8 weeks after the initial hysteroscopy, the adhesion recurrence rate in women who had an intrauterine balloon for 28 days (20%) was significantly (P < 0.01) lower than that of women who had the balloon for 14 days (55%) or 7 days (36.8%).
Placing an intrauterine balloon for 28 days instead of 7 or 14 days after hysteroscopic adhesiolysis resulted in a greater reduction in the recurrence rate of adhesions. However, the study was underpowered to address whether the ongoing pregnancy rate could be improved by keeping the balloon in the uterine cavity for a longer period of time.
在宫腔镜粘连松解术后不同时间（7、14 或 28 天）放置宫内球囊是否会影响宫腔粘连的复发？
这是一项为期 12 个月的前瞻性随机对照试验，共纳入 138 例患者，术后随访 15 个月。主要观察指标为第三次宫腔镜检查时粘连再形成的发生率。
在初始宫腔镜检查后 8 周的第三次宫腔镜检查中，宫内球囊放置 28 天的患者（20%）粘连复发率明显低于放置 14 天（55%）或 7 天（36.8%）的患者（P < 0.01）。
与宫腔镜粘连松解术后放置 7 天或 14 天相比，放置宫内球囊 28 天可显著降低粘连的复发率。然而，本研究的效力不足，无法确定延长球囊在宫腔内放置时间是否能提高持续妊娠率。
