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儿童二尖瓣位置下基于支架瓣膜的外科植入的三维建模。

Three-Dimensional Modeling of Surgically Implanted Stent-Based Valves in the Mitral Position in Children.

机构信息

Department of Cardiac Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Department of Anesthesia and Critical Care, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

出版信息

Ann Thorac Surg. 2020 Aug;110(2):670-675. doi: 10.1016/j.athoracsur.2020.02.020. Epub 2020 Mar 18.

Abstract

PURPOSE

In children with a mitral annulus too small to accommodate traditional prostheses, surgical implantation of stent-based valves is a promising option. However no reliable preoperative methods exist to guide patient selection, device sizing, and positioning. We describe a novel methodology to visualize and quantify device fit in 3-dimensional echocardiogram (3DE)-derived heart models.

DESCRIPTION

Heart models were created from existing preoperative 3DEs using custom software. Valve models were virtually implanted into the models, and both device fit and left ventricular outflow tract (LVOT) area were quantified.

EVALUATION

The 3DEs of 3 patients who underwent Melody valve placement in the mitral position were retrospectively modeled: 1 with LVOT obstruction, 1 with perivalvar leak, and 1 without complications. In all cases 2-dimensional measurements underestimated 3D annular dimensions, and the patient with clinical LVOT obstruction had the lowest predicted LVOT area-to-aortic area ratio (0.5).

CONCLUSIONS

3DE-based preoperative modeling of surgical implantation of stent-based valves in the mitral position may improve quantification of mitral valve dimensions and inform risk stratification for potential LVOT obstruction.

摘要

目的

对于二尖瓣瓣环过小而无法容纳传统假体的儿童,支架瓣膜的外科植入是一种很有前途的选择。然而,目前尚无可靠的术前方法来指导患者选择、器械尺寸选择和定位。我们描述了一种新的方法,用于在基于三维超声心动图(3DE)的心脏模型中可视化和量化器械适配。

方法

使用定制软件从现有的术前 3DE 创建心脏模型。将瓣膜模型虚拟植入模型中,并量化器械适配和左心室流出道(LVOT)面积。

评估

回顾性地对 3 名在二尖瓣位置接受 Melody 瓣膜植入的患者的 3DE 进行建模:1 例存在 LVOT 梗阻,1 例存在瓣周漏,1 例无并发症。在所有情况下,二维测量均低估了 3D 瓣环尺寸,且临床存在 LVOT 梗阻的患者的预测 LVOT 面积与主动脉面积比最低(0.5)。

结论

基于 3DE 的二尖瓣位置支架瓣膜外科植入术的术前建模,可能有助于二尖瓣尺寸的量化,并为潜在的 LVOT 梗阻分层风险提供信息。

相似文献

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Assessment of the Melody valve in the mitral position in young children by echocardiography.超声心动图评估婴幼儿二尖瓣位置的 Melody 瓣膜。
J Thorac Cardiovasc Surg. 2017 Jan;153(1):153-160.e1. doi: 10.1016/j.jtcvs.2016.07.017. Epub 2016 Jul 25.

本文引用的文献

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Results after mitral valve replacement with mechanical prostheses in young children.小儿二尖瓣置换术后的结果。
J Thorac Cardiovasc Surg. 2010 May;139(5):1189-96, 1196.e1-2. doi: 10.1016/j.jtcvs.2009.10.038. Epub 2010 Mar 11.

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