Yao Z H, Wu A R
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1988 May;10(3):230-2.
From Mar. 1958 to Dec. 1985, 13547 patients with cervical cancer in stages I-III were treated by radiotherapy in our hospital. Supraclavicular lymph node metastasis developed in 219 (1.62%), 83.1% on the left, 7.7% on the right and 9.13% bilateral. 61.2% of the metastasis occurred within 2 years and 86.75% within 5 years after radiotherapy. The majority of these patients (88.3%, 191/215), except 4 who are still being followed, had died within 1.5 years of metastasis with a mean survival of 9.3 months. If radiotherapy in adequate dose is given to the supraclavicular metastatic area, the mean survival can be prolonged for 3.7 months. The prognosis is very poor for these patients no matter what the clinical stage is or when the metastasis develops. The more advanced clinical stage, the higher metastasis rate (P less than 0.001). In this series, 47/219 (21.5%) were found to have concurrent metastasis to the other organs.
1958年3月至1985年12月，我院对13547例Ⅰ - Ⅲ期宫颈癌患者进行了放射治疗。发生锁骨上淋巴结转移的有219例（1.62%），其中左侧转移占83.1%，右侧转移占7.7%，双侧转移占9.13%。61.2%的转移发生在放疗后2年内，86.75%发生在5年内。这些患者中的大多数（88.3%，191/215），除4例仍在随访中外，在转移后1.5年内死亡，平均生存期为9.3个月。如果对锁骨上转移区域给予足够剂量的放疗，平均生存期可延长3.7个月。无论临床分期如何或转移何时发生，这些患者的预后都很差。临床分期越晚，转移率越高（P＜0.001）。在本系列中，发现47/219（21.5%）同时伴有其他器官转移。
