Rayamajhi Dheeraj, Roy Sudipto
Institute of Molecular and Cell Biology, Proteos, 61 Biopolis Drive, Singapore 138673; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543.
Institute of Molecular and Cell Biology, Proteos, 61 Biopolis Drive, Singapore 138673; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543; Department of Pediatrics, Yong Loo Ling School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119288.
Trends Cell Biol. 2020 Apr;30(4):259-262. doi: 10.1016/j.tcb.2020.02.003. Epub 2020 Feb 27.
Esoteric organelles called deuterosomes have been implicated in the explosive production of hundreds of basal bodies in multiciliated cells (MCCs). A new study by Meunier, Holland, and colleagues now shows that deuterosomes are dispensable, re-igniting the quest for mechanisms driving basal body biogenesis in this specialized ciliated cell type.
一种名为双体的神秘细胞器与多纤毛细胞(MCCs)中数百个基体的快速产生有关。现在,Meunier、Holland及其同事进行的一项新研究表明,双体并非不可或缺,这再次引发了人们对驱动这种特殊纤毛细胞类型中基体生物发生机制的探索。