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左冠状动脉起源于肺动脉:一种确定的手术适应证。

Anomalous origin of the left coronary artery from the pulmonary artery: A surgical certainty.

机构信息

4th Year MBBS Student, Aga Khan University Medical College, Karachi, Pakistan.

Department of Pediatric Cardiac Services, National Institute of Cardiovascular Diseases, Karachi, Pakistan.

出版信息

J Pak Med Assoc. 2020 Mar;70(3):561-564. doi: 10.5455/JPMA.34200.

Abstract

This study aims to assess the clinical presentation and the outcomes of a surgical correction of an anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA). A retrospective review was carried out on the charts of six patients admitted for ALCAPA surgery at Aga Khan University Hospital, Karachi from March 2017 to May 2018.Dyspnoea, palpitation, poor feeding, fatiguability, pallor and a murmur of mitral regurgitation were the main presenting features. The pre-operative median left ventricular ejection fraction (LVEF) was 64%. Coronary reimplantation was performed in all the patients with a mitral valve repair being done in only one patient. The mea n LV EF was 66 .3%,p ost- ope rativel y. Mitra l regurgitation (MR) improved in patients post-operatively with trace in 2 patients and mild MR in one. Surgical correction by coronary re-implantation yields favourable outcomes in ALCAPA and significantly reduces the morbidity and mortality rates associated with the disease.

摘要

本研究旨在评估左冠状动脉异常起源于肺动脉(ALCAPA)的手术矫正的临床表现和结果。对 2017 年 3 月至 2018 年 5 月在卡拉奇 Aga Khan 大学医院接受 ALCAPA 手术的 6 名患者的病历进行了回顾性分析。呼吸困难、心悸、喂养不良、乏力、苍白和二尖瓣反流杂音是主要表现特征。术前左心室射血分数(LVEF)中位数为 64%。所有患者均进行了冠状动脉再植入术,仅 1 例患者进行了二尖瓣修复术。术后平均 LVEF 为 66.3%。术后二尖瓣反流(MR)改善,2 例患者为微量反流,1 例患者为轻度 MR。冠状动脉再植入术的手术矫正可获得 ALCAPA 的良好结果,并显著降低与该疾病相关的发病率和死亡率。

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