Song Lei, Jiang Yuan-Xu, Zhang Zhen, Gui Yong-Yuan, Zhou Xiao-Yu, Yu Da-Gang
Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China.
Chem Commun (Camb). 2020 Jul 28;56(60):8355-8367. doi: 10.1039/d0cc00547a.
Carbon dioxide (CO2) is an ideal one-carbon source owing to its nontoxicity, abundance, availability, and recyclability. Although the thermodynamic stability and kinetic inertness of CO2 bring its utilization challenges, many groups have achieved significant progress in the utilization of CO2 to synthesize valuable carbonyl-containing compounds, which could be also generated via oxidative carbonylation of C-H bonds with CO. As CO2 has a higher oxidation state than CO, it could be considered as a combination of CO and oxidant (CO2 = CO + [O]), thus providing a safe, redox-neutral and economic strategy. In this Feature Article, we have summarized the recent advances in carbonylation of C-H bonds with CO2 based on this concept. The plausible mechanisms of such reactions and future of this field are also discussed.
二氧化碳（CO₂）因其无毒、储量丰富、易于获取且可循环利用，是一种理想的单碳源。尽管CO₂的热力学稳定性和动力学惰性给其利用带来了挑战，但许多研究团队在利用CO₂合成有价值的含羰基化合物方面取得了显著进展，这些化合物也可通过C-H键与CO的氧化羰基化反应生成。由于CO₂的氧化态高于CO，它可被视为CO与氧化剂的组合（CO₂ = CO + [O]），从而提供了一种安全、氧化还原中性且经济的策略。在这篇专题文章中，我们基于这一概念总结了CO₂参与的C-H键羰基化反应的最新进展。同时也讨论了此类反应可能的机理以及该领域的未来发展。
