Queen's University, Department of Emergency Medicine, Kingston, ON.
Kingston Health Sciences Centre, Kingston, ON.
CJEM. 2020 Mar;22(2):149-151. doi: 10.1017/cem.2019.452.
Soft tissue abscess used to be an easy emergency department (ED) presentation: perform an incision and drainage (I + D) and discharge your patient. Times have changed. Methicillin-resistant Staphylococcus aureus (MRSA) is now a major cause of soft tissue abscess in ED patients. MRSA is, by definition, resistant to cloxacillin and cephalosporins. Almost all Canadian strains are susceptible to vancomycin and linezolid. MRSA strains are variably susceptible to trimethoprim-sulfamethoxazole (TMP-SMX), tetra/doxycycline, and clindamycin, with pooled Canadian clindamycin resistance just over 40%.
软组织脓肿曾经是急诊科（ED）常见的急症：进行切开引流（I&D），然后让患者出院。但时代已经变了。耐甲氧西林金黄色葡萄球菌（MRSA）现在是 ED 患者软组织脓肿的主要病因。根据定义，MRSA 对氯唑西林和头孢菌素具有耐药性。几乎所有加拿大菌株对万古霉素和利奈唑胺敏感。MRSA 菌株对甲氧苄啶-磺胺甲恶唑（TMP-SMX）、四环素/多西环素和克林霉素的敏感性不同，加拿大克林霉素耐药率略高于 40%。
