Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine.
Clin Nucl Med. 2020 May;45(5):423-425. doi: 10.1097/RLU.0000000000003004.
Ga-pentixafor PET/CT in a 66-year-old woman with newly diagnosed multiple myeloma showed extensive disease in bone and bone marrow. After 6 cycles of chemotherapy, the patient was in complete remission but complained of fever and coughing. Follow-up Ga-pentixafor PET/CT showed significantly reduced uptake in bone and bone marrow, consistent with her clinical outcome of myeloma. However, patches, nodules, and ground-grass opacities in bilateral lungs with moderate to intense uptake of Ga-pentixafor were noted. The histopathology of the biopsy for the pulmonary nodule confirmed pulmonary cryptococcosis.
66 岁女性新诊断多发性骨髓瘤患者，Ga- 戊二烯 PET/CT 显示骨骼和骨髓广泛受累。经过 6 个周期的化疗后，患者达到完全缓解，但出现发热和咳嗽。后续 Ga- 戊二烯 PET/CT 显示骨骼和骨髓摄取明显减少，与多发性骨髓瘤的临床缓解结果一致。然而，双侧肺部出现斑片、结节和磨玻璃影，Ga- 戊二烯摄取中度至强烈。肺部结节活检的组织病理学证实为肺隐球菌病。
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