Taani Murad H, Zabler Bev, Fendrich Michael, Schiffman Rachel
College of Nursing, University of Wisconsin-Milwaukee, 1921 East Hartford Avenue, Milwaukee, WI, 53211, United States.
School of Social Work, University of Connecticut, 38 Prospect Street, Harford, CT, 06103, United States.
Contemp Clin Trials Commun. 2020 Jan 22;17:100533. doi: 10.1016/j.conctc.2020.100533. eCollection 2020 Mar.
Recruitment and retention of low-income African Americans in clinical trials is challenging. This paper reports recruitment and retention strategies that yielded high rates for both in a clinical trial pilot to improve hypertension self-management among low-income African Americans. The study successfully recruited 96.7% (59 of 61 participants) within a seven month period. Retention rates for the 1, 3, and 6-month post-baseline assessment visits were 91.5%, 88.1%, and 83.1%, respectively. Recruitment and retention strategies include two grounded in previous literature: a culturally sensitive and diverse research team and use of incentives. Four additional strategies were developed for this study to meet the needs of the study site and participants, which included: study site collaboration; ongoing communications; responding to the clinical environment; and addressing participants' health literacy levels. A discussion of key recruitment and retention strategies and suggestions for future studies focused on low-income African American participants ensues.
在临床试验中招募和留住低收入非裔美国人具有挑战性。本文报告了在一项旨在改善低收入非裔美国人高血压自我管理的临床试验试点中，实现高招募率和高留存率的策略。该研究在七个月内成功招募了96.7%（61名参与者中的59名）。基线后1个月、3个月和6个月评估访视的留存率分别为91.5%、88.1%和83.1%。招募和留存策略包括基于以往文献的两个策略：具有文化敏感性和多样性的研究团队以及使用激励措施。为满足研究地点和参与者的需求，本研究还制定了另外四个策略，包括：研究地点合作；持续沟通；应对临床环境；以及解决参与者的健康素养水平问题。随后讨论了关键的招募和留存策略以及针对未来以低收入非裔美国参与者为重点的研究的建议。
