• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Use of lyoprotectants in the freeze-drying of a model protein, ribonuclease A.

作者信息

Townsend M W, DeLuca P P

出版信息

J Parenter Sci Technol. 1988 Nov-Dec;42(6):190-9.

PMID:3221279
Abstract
摘要

相似文献

1
Use of lyoprotectants in the freeze-drying of a model protein, ribonuclease A.冻干模型蛋白核糖核酸酶A时冻干保护剂的应用。
J Parenter Sci Technol. 1988 Nov-Dec;42(6):190-9.
2
Freeze-drying of proteins: some emerging concerns.蛋白质的冷冻干燥:一些新出现的问题。
Biotechnol Appl Biochem. 2004 Apr;39(Pt 2):165-77. doi: 10.1042/BA20030133.
3
Rapid optimization of protein freeze-drying formulations using ultra scale-down and factorial design of experiment in microplates.使用超微缩技术和微孔板实验的析因设计快速优化蛋白质冻干制剂
Biotechnol Bioeng. 2009 Dec 1;104(5):957-64. doi: 10.1002/bit.22448.
4
Investigation of nanocapsules stabilization by amorphous excipients during freeze-drying and storage.冻干和储存过程中无定形辅料对纳米胶囊的稳定作用研究。
Eur J Pharm Biopharm. 2006 Jun;63(2):87-94. doi: 10.1016/j.ejpb.2006.01.015. Epub 2006 Apr 18.
5
The effect of the structure of frozen material upon the course of freeze-drying and upon some properties of the lyophilizate.冷冻材料的结构对冷冻干燥过程及冻干产品某些性质的影响。
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl. 1979;22(1):97-104.
6
Freeze drying of human serum albumin (HSA) nanoparticles with different excipients.使用不同辅料对人血清白蛋白(HSA)纳米颗粒进行冷冻干燥。
Int J Pharm. 2008 Nov 3;363(1-2):162-9. doi: 10.1016/j.ijpharm.2008.07.004. Epub 2008 Jul 15.
7
Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelles with disulfide crosslinked cores to the liver.用于将具有二硫键交联核心的聚乙二醇化多聚体胶束体内基因递送至肝脏的冻干制剂。
J Control Release. 2005 Dec 5;109(1-3):15-23. doi: 10.1016/j.jconrel.2005.09.043. Epub 2005 Nov 17.
8
Polymers protect lactate dehydrogenase during freeze-drying by inhibiting dissociation in the frozen state.聚合物在冷冻干燥过程中通过抑制乳酸脱氢酶在冷冻状态下的解离来保护它。
Arch Biochem Biophys. 1996 Aug 15;332(2):231-8. doi: 10.1006/abbi.1996.0337.
9
Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying.蔗糖和海藻糖在超临界流体干燥和冷冻干燥过程中对蛋白质稳定性的不同影响。
Eur J Pharm Sci. 2006 Mar;27(4):336-45. doi: 10.1016/j.ejps.2005.11.003. Epub 2005 Dec 9.
10
The effect of the reconstitution medium on aggregation of lyophilized recombinant interleukin-2 and ribonuclease A.复溶介质对冻干重组白细胞介素-2和核糖核酸酶A聚集的影响。
Pharm Res. 1996 Apr;13(4):643-6. doi: 10.1023/a:1016074811306.

引用本文的文献

1
Effect of cryoprotection on particle size stability and preservation of chitosan nanoparticles with and without hyaluronate or alginate coating.冷冻保护对有或无透明质酸盐或藻酸盐涂层的壳聚糖纳米颗粒粒径稳定性及保存的影响。
Saudi Pharm J. 2017 Sep;25(6):861-867. doi: 10.1016/j.jsps.2016.12.008. Epub 2017 Jan 10.
2
Investigation of Color in a Fusion Protein Using Advanced Analytical Techniques: Delineating Contributions from Oxidation Products and Process Related Impurities.使用先进分析技术对融合蛋白中的颜色进行研究:确定氧化产物和与工艺相关杂质的贡献。
Pharm Res. 2016 Apr;33(4):932-41. doi: 10.1007/s11095-015-1839-3. Epub 2015 Dec 10.
3
Studies towards the stabilisation of a mushroom phytase produced by submerged cultivation.
关于通过深层培养生产的一种蘑菇植酸酶稳定性的研究。
Protein J. 2015 Oct;34(5):367-79. doi: 10.1007/s10930-015-9631-0.
4
Stability of infectious human coronavirus NL63.人类传染性冠状病毒NL63的稳定性
J Virol Methods. 2014 Sep 1;205:87-90. doi: 10.1016/j.jviromet.2014.04.001. Epub 2014 Apr 18.
5
A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease.美拉德反应与蛋白质糖基化的质谱分析视角:探究慢性疾病的发病机制
J Proteome Res. 2009 Feb;8(2):754-69. doi: 10.1021/pr800858h.
6
Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide).基于两亲性二嵌段共聚物聚(N-乙烯基-2-吡咯烷酮)-嵌段-聚(D,L-丙交酯)的新型聚合物胶束。
Pharm Res. 2001 Mar;18(3):323-8. doi: 10.1023/a:1011054930439.
7
Effect of initial buffer composition on pH changes during far-from-equilibrium freezing of sodium phosphate buffer solutions.初始缓冲液组成对磷酸钠缓冲溶液远非平衡态冷冻过程中pH变化的影响。
Pharm Res. 2001 Jan;18(1):90-7. doi: 10.1023/a:1011082911917.
8
Freeze-concentration separates proteins and polymer excipients into different amorphous phases.冷冻浓缩将蛋白质和聚合物辅料分离成不同的非晶相。
Pharm Res. 2000 Oct;17(10):1316-22. doi: 10.1023/a:1026412107574.
9
Maltodextrins as lyoprotectants in the lyophilization of a model protein, LDH.麦芽糖糊精作为模型蛋白乳酸脱氢酶冻干过程中的冻干保护剂。
Pharm Res. 1996 Jan;13(1):146-50. doi: 10.1023/a:1016006106821.
10
Stability of beta-galactosidase, a model protein drug, is related to water mobility as measured by 17O nuclear magnetic resonance (NMR).作为一种模型蛋白药物,β-半乳糖苷酶的稳定性与通过17O核磁共振(NMR)测量的水流动性有关。
Pharm Res. 1993 Jan;10(1):103-8. doi: 10.1023/a:1018933315538.