McDonald R K, Walker M, Legendre A M, vanEe R T, Gompf R E
Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State 39762.
J Vet Intern Med. 1988 Apr-Jun;2(2):103-7. doi: 10.1111/j.1939-1676.1988.tb02802.x.
Four dogs with metastatic seminoma were treated with cesium 137 teleradiotherapy. Minimum total tumor dose ranged from 17 to 40 gray (Gy) and was usually given through bilateral opposing sublumbar ports in eight to ten fractions, with three fractions given weekly. The tumor regressed in all four dogs. The first dog (case 1) was free of tumor and died of non-tumor related causes at 57 months. The second dog (case 2) was free of tumor but was euthanatized at 37 months for a limb fracture. The third dog (case 3) was euthanatized for undertermined pulmonary disease 43 months after radiotherapy. The fourth dog (case 4) was euthanatized 6 months following radiotherapy because of transitional cell carcinoma and renal failure. No evidence of seminoma was found at necropsy. Radiotherapy was shown to be effective treatment for seminoma with regional metastasis.
四只患有转移性精原细胞瘤的犬接受了铯 137 远距离放射治疗。最小总肿瘤剂量为 17 至 40 格雷（Gy），通常通过双侧对置的腰下部野分八至十次给予，每周三次。所有四只犬的肿瘤均消退。第一只犬（病例 1）无肿瘤，于 57 个月时死于非肿瘤相关原因。第二只犬（病例 2）无肿瘤，但因肢体骨折于 37 个月时实施安乐死。第三只犬（病例 3）在放疗后 43 个月因不明肺部疾病实施安乐死。第四只犬（病例 4）在放疗后 6 个月因移行细胞癌和肾衰竭实施安乐死。尸检未发现精原细胞瘤证据。放射治疗被证明是治疗伴有区域转移的精原细胞瘤的有效方法。
