Siniscalchi, Department of Neurology and Stroke Unit, "Annunziata" Hospital, Cosenza, Italy. Perrotta, Department of Neuroradiology, "Annunziata" Hospital, Cosenza, Italy. Lochner, Department of Neurology, Saarland University Medical Center, Homburg, Germany. Gallelli, Chair of Pharmacology, Department of Health Science, School of Medicine, University of Catanzaro, Clinical Pharmacology Unit, Mater Domini University Hospital, Catanzaro, Italy.
Psychopharmacol Bull. 2020 Mar 12;50(1):44-47.
Carotid artery dissection represents a well-recognized cause of hypoglossal nerve paralysis even if it is less known the cause of acute tongue swelling. We report a 42-year old men who presented to our observation with acute tongue swelling and atrophy of left side of tongue from a hypoglossal nerve injury. A magnetic resonance imaging revealed a denervation of the left half of the tongue from a hypoglossal nerve injury due to left extracranial internal carotid artery (ICA) dissection, without evidence of ischemic stroke. The urine toxicology screen test revealed a positivity for cocaine. This case report suggest to perform in young patient a toxicological drug screening test in presence of ICA dissection with hypoglossal nerve injury and an acute tongue swelling. However clinical data must be performed to validate this observation and to analyze the negative effect of cocaine use.
颈动脉夹层是舌下神经麻痹的一个公认原因,尽管急性舌肿胀的原因不太清楚。我们报告了 1 例 42 岁男性,因舌下神经损伤出现急性舌肿胀和左侧舌萎缩来我院就诊。磁共振成像显示左侧颈内动脉(ICA)夹层导致左侧舌下神经损伤引起的舌半侧失神经支配,无缺血性脑卒中证据。尿液毒理学筛查试验显示可卡因阳性。本病例报告提示,对于颈内动脉夹层合并舌下神经损伤和急性舌肿胀的年轻患者,应进行毒理学药物筛查。但是,必须进行临床数据来验证这一观察结果,并分析可卡因使用的负面影响。