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合成生物学:从首个合成细胞看其现状与未来发展。

Synthetic biology: From the first synthetic cell to see its current situation and future development.

作者信息

Zhang LiuYan, Chang SuHua, Wang Jing

机构信息

Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101 China.

出版信息

Chin Sci Bull. 2011;56(3):229-237. doi: 10.1007/s11434-010-4304-z. Epub 2011 Jan 26.

Abstract

Synthetic biology is an emerging field, which, since its birth, has shown great value and potential in many fields including medicine, energy, environment and agriculture. It is also important for the study of the origin and evolution of life. Since the publication of the first synthetic cell in May, 2010, synthetic biology again attracts high attention and leads to extensive discussions all over the world. There have been a number of researches and achievements on synthetic biology in the United States and European countries. While in China, so far there is no systematic research on synthetic biology. In order to promote the development of this new discipline in China, we organized this review to systematically introduce the concept and research content of synthetic biology, summarize the achievements, and investigate the current situation in both China and abroad. We also analyzed the opportunities and challenges in synthetic biology, and looked forward to the future development of synthetic biology, especially its future development in China.

摘要

合成生物学是一个新兴领域,自诞生以来,已在医学、能源、环境和农业等众多领域展现出巨大价值和潜力。它对于生命起源与进化的研究也很重要。自2010年5月首个合成细胞问世以来,合成生物学再次引起全球高度关注并引发广泛讨论。美国和欧洲国家在合成生物学方面已有诸多研究与成果。而在中国,迄今为止尚无对合成生物学的系统研究。为推动这一新兴学科在中国的发展,我们组织了这篇综述,系统介绍合成生物学的概念和研究内容,总结成果,并调研国内外现状。我们还分析了合成生物学面临的机遇与挑战,展望了合成生物学的未来发展,尤其是其在中国的未来发展。

相似文献

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Synthetic biology: an emerging engineering discipline.合成生物学:一门新兴的工程学科。
Annu Rev Biomed Eng. 2012;14:155-78. doi: 10.1146/annurev-bioeng-071811-150118. Epub 2012 May 7.

本文引用的文献

1
How to make a minimal genome for synthetic minimal cell.如何构建合成最小细胞的最小基因组。
Protein Cell. 2010 May;1(5):427-34. doi: 10.1007/s13238-010-0064-4. Epub 2010 Jun 4.
6
Synthetic biology: applications come of age.合成生物学:应用走向成熟。
Nat Rev Genet. 2010 May;11(5):367-79. doi: 10.1038/nrg2775.
10
Five hard truths for synthetic biology.合成生物学的五个残酷现实。
Nature. 2010 Jan 21;463(7279):288-90. doi: 10.1038/463288a.

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