人类ABO基因的转录调控。 - Suppr

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超能文献

Human ABO gene transcriptional regulation.

作者信息

Kominato Yoshihiko, Sano Rie, Takahashi Yoichiro, Hayakawa Akira, Ogasawara Kenichi

机构信息

Department of Legal Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.

Japanese Red Cross Central Blood Institute, Tokyo, Japan.

出版信息

Transfusion. 2020 Apr;60(4):860-869. doi: 10.1111/trf.15760. Epub 2020 Mar 26.

DOI:10.1111/trf.15760

PMID:32216153

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7187371/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f72/7187371/a99fe35d2043/TRF-60-860-g001.jpg

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RUNX1 mutation in a patient with myelodysplastic syndrome and decreased erythrocyte expression of blood group A antigen.患者患有骨髓增生异常综合征，红细胞表面的 A 血型抗原表达减少，检测到 RUNX1 基因突变。

Transfusion. 2020 Jan;60(1):184-196. doi: 10.1111/trf.15628. Epub 2019 Dec 16.

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Is B 5.8 specific to the Japanese population?

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A novel mutation +5904 C>T of RUNX1 site in the erythroid cell-specific regulatory element decreases the ABO antigen expression in Chinese population.红细胞特异性调控元件中RUNX1位点的新型突变+5904 C>T降低了中国人群中的ABO抗原表达。

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ABO genotyping with next-generation sequencing to resolve heterogeneity in donors with serology discrepancies.采用新一代测序技术进行ABO基因分型以解决血清学结果不一致的供者的异质性问题。

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