IRCCS, Istituto Giannina Gaslini, DINOGMI Department University of Genoa, Via Gaslini 5, 16148, Genoa, Italy.
Department of Neonatology, Erasmus Medical Center University, Sophia Children's Hospital, Rotterdam, The Netherlands.
Pediatr Res. 2020 Mar;87(Suppl 1):13-24. doi: 10.1038/s41390-020-0780-2.
Germinal matrix-intraventricular haemorrhage (GMH-IVH), periventricular haemorrhagic infarction (PHI) and its complication, post-haemorrhagic ventricular dilatation (PHVD), are still common neonatal morbidities in preterm infants that are highly associated with adverse neurodevelopmental outcome. Typical cranial ultrasound (CUS) findings of GMH-IVH, PHI and PHVD, their anatomical substrates and underlying mechanisms are discussed in this paper. Furthermore, we propose a detailed descriptive classification of GMH-IVH and PHI that may improve quality of CUS reporting and prediction of outcome in infants suffering from GMH-IVH/PHI.
脑室内出血(GMH-IVH)、脑室内出血伴脑实质出血(PHI)及其并发症出血后脑积水(PHVD)仍然是早产儿常见的新生儿并发症,与不良神经发育结局高度相关。本文讨论了 GMH-IVH、PHI 和 PHVD 的典型头颅超声(CUS)表现、解剖基础和潜在机制。此外,我们提出了 GMH-IVH 和 PHI 的详细描述性分类,这可能有助于提高 CUS 报告的质量,并预测 GMH-IVH/PHI 患儿的结局。