Department of Epidemiology and Biostatistics, School of Public Health, Indiana University, Bloomington.
Department of Environmental Health, School of Public Health, Indiana University, Bloomington.
Ann Epidemiol. 2020 Apr;44:38-44.e1. doi: 10.1016/j.annepidem.2020.01.010. Epub 2020 Feb 28.
The purpose of this study was to determine the association between household food insecurity (HFI) and elevated antepartum depressive symptoms (EADS) in the National Children's Study, 2009-2014, as well as standardize our results to the U.S. pregnant population.
HFI was collected at participants' baseline visits using the U.S. Household Food Security Survey Module; antepartum depression symptoms were collected twice during pregnancy using the Center for Epidemiologic Study Depression scale. Generalized estimating equations for binary outcomes were used to estimate the association between HFI and EADS. Inverse probability weighting was used to generalize the effect to the U.S. population using the National Health and Nutrition Examination Survey.
Among 746 participants, 20.6% were food insecure. Women who were food insecure were 3.39 times (95% confidence interval: 1.73, 6.62) as likely to report EADS compared with women who were food secure. This estimate was marginally strengthened in a weighted analysis (odds ratio: 3.68; 95% confidence interval: 1.43, 9.43).
This study suggests that women who are food insecure are at a greater risk of EADS, and HFI should be evaluated when assessing antepartum depression.
本研究旨在确定 2009-2014 年全国儿童研究中家庭食物不安全（HFI）与产前抑郁症状升高（EADS）之间的关联，并将我们的结果标准化到美国孕妇人群。
使用美国家庭食物安全调查模块在参与者的基线访视中收集 HFI；使用流行病学研究抑郁量表在妊娠期间两次收集产前抑郁症状。使用二项结果的广义估计方程来估计 HFI 与 EADS 之间的关联。使用逆概率加权法，使用国家健康和营养检查调查来将该效应推广到美国人群。
在 746 名参与者中，20.6%的人食物不安全。与食物安全的女性相比，食物不安全的女性报告 EADS 的可能性高 3.39 倍（95%置信区间：1.73，6.62）。在加权分析中，这一估计略有增强（比值比：3.68；95%置信区间：1.43，9.43）。
本研究表明，食物不安全的女性患 EADS 的风险更高，在评估产前抑郁时应评估 HFI。
