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低资源环境下有复苏风险的新生儿心率测定:一项随机对照试验。

Heart Rate Determination in Newborns at Risk for Resuscitation in a Low-Resource Setting: A Randomized Controlled Trial.

机构信息

Independent statistician, Solagna, Italy.

Department of Woman and Child Health, Università Cattolica del Sacro Cuore, Roma, Italy.

出版信息

J Pediatr. 2020 Jun;221:88-92.e1. doi: 10.1016/j.jpeds.2020.02.026. Epub 2020 Mar 25.

Abstract

OBJECTIVE

To compare 2 different methods (auscultation with a stethoscope and umbilical cord palpation) of heart rate (HR) estimation in newborns at risk for resuscitation in a low-resource setting.

STUDY DESIGN

Sixty newborns at risk for resuscitation born at the St. Luke Catholic Hospital in Wolisso (Ethiopia) were randomized to HR assessment by auscultation using a stethoscope or umbilical cord palpation. HR was assessed at 60, 90, 120 seconds, and 5 minutes of life. The primary outcome was the agreement of HR obtained by auscultation or palpation compared with the HR determined by electrocardiogram.

RESULTS

Mean difference between auscultation using a stethoscope and electrocardiogram was -13 bpm, -4 bpm, -6 bpm, and -10 bpm at 60, 90, 120 seconds, and at 5 minutes of life. Mean difference between palpation and electrocardiogram of was -20 bpm, -25 bpm, -23 bpm, and -31 bpm at 60, 90, 120 seconds, and at 5 minutes of life. The magnitude of the difference between auscultation and electrocardiogram was lower than that between palpation and electrocardiogram over time (P = .007). HR range was correctly identified in 14 out of 16 measurements (87%) with HR <100 bpm.

CONCLUSION

HR assessment by auscultation was more accurate compared with cord palpation, but both may provide adequate clinical information to healthcare providers in terms of HR ranges. The clinical advantage of providing a stethoscope in low-resource settings remains to be established.

TRIAL REGISTRATION

ClinicalTrials.gov: NCT03854435.

摘要

目的

比较听诊与脐脉触诊 2 种方法在资源匮乏环境下对有复苏风险新生儿进行心率(HR)评估的效果。

研究设计

60 例有复苏风险的新生儿出生于埃塞俄比亚 Wolisso 的圣卢克天主教医院,随机分为听诊组(使用听诊器听诊)和触诊组(脐脉触诊)。在出生后 60、90、120 秒和 5 分钟时评估 HR,主要结局是比较听诊和触诊与心电图所测 HR 的一致性。

结果

听诊与心电图相比,平均差值分别为-13 bpm、-4 bpm、-6 bpm 和-10 bpm,在出生后 60、90、120 秒和 5 分钟时;触诊与心电图相比,平均差值分别为-20 bpm、-25 bpm、-23 bpm 和-31 bpm,在出生后 60、90、120 秒和 5 分钟时。随着时间的推移,听诊与心电图之间的差值变化幅度小于触诊与心电图之间的差值(P=0.007)。在 HR<100 bpm 的 16 次测量中,听诊法有 14 次(87%)正确识别了 HR 范围。

结论

与脐脉触诊相比,听诊法评估 HR 更准确,但在 HR 范围方面,两种方法都能为医护人员提供足够的临床信息。在资源匮乏环境下提供听诊器是否具有临床优势还有待确定。

试验注册

ClinicalTrials.gov:NCT03854435。

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