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患有胃食管套叠犬的特征及长期预后

Characteristics and long-term outcomes of dogs with gastroesophageal intussusception.

作者信息

Grimes Janet A, Fleming Jeremy T, Singh Ameet, Campbell Bonnie G, Hedlund Cheryl S, Tobias Karen M, Arai Shiori, Ham Kathleen M, Repellin Raphael, Schroeder Regina, Sumner Julia P, Abrams Brittany, Boudreau Bianca, Lewis Beth, Wallace Mandy L

出版信息

J Am Vet Med Assoc. 2020 Apr 15;256(8):914-920. doi: 10.2460/javma.256.8.914.

Abstract

OBJECTIVE

To determine long-term outcomes and factors associated with those outcomes in dogs with gastroesophageal intussusception (GEI).

ANIMALS

36 dogs with GEI evaluated at 16 veterinary hospitals from January 2000 through January 2018.

PROCEDURES

Medical records of included dogs were reviewed to collect information regarding signalment, clinical signs, physical examination findings, blood work and diagnostic imaging results, surgical findings, and outcome. Factors were evaluated for associations with various outcomes.

RESULTS

Median age of dogs with GEI was 13.2 months, and males (72% [26/36]) and German Shepherd Dogs (33% [12/36]) were most common. Vomiting (67% [24/36]) and regurgitation (33% [12/36]) were the most common clinical signs. Ten of 36 (28%) dogs were euthanized without treatment, and 26 (72%) underwent treatment (25 surgically and 1 endoscopically). Twenty-three of the 26 (88%) treated dogs survived to discharge; median survival time was 995 days. At last follow-up, 15 of the 23 (65%) surviving dogs remained alive and 8 (35%) had died for reasons related to persistent regurgitation (n = 6) or reasons unrelated to GEI (2). Of the 10 dogs for which owners were contacted, 7 had persistent regurgitation, the severity of which was reduced through managed feedings. Dogs with acute (≤ 7 days) clinical signs or a previous diagnosis of megaesophagus were more likely to have persistent regurgitation than were dogs without these factors.

CONCLUSIONS AND CLINICAL RELEVANCE

Treatment should be considered for dogs with GEI given the high rate of survival to discharge and median survival time. Although persistent regurgitation was common after treatment, a satisfactory outcome was possible with medical management, including managed feedings and medications.

摘要

目的

确定患有胃食管套叠(GEI)的犬的长期预后以及与这些预后相关的因素。

动物

2000年1月至2018年1月期间在16家兽医医院评估的36只患有GEI的犬。

方法

回顾纳入犬的病历,收集有关信号、临床症状、体格检查结果、血液检查和诊断成像结果、手术结果及预后的信息。评估各因素与不同预后的相关性。

结果

患有GEI的犬的中位年龄为13.2个月,最常见的是雄性犬(72%[26/36])和德国牧羊犬(33%[12/36])。呕吐(67%[24/36])和反流(33%[12/36])是最常见的临床症状。36只犬中有10只(28%)未经治疗实施安乐死,26只(72%)接受了治疗(25只接受手术,1只接受内镜治疗)。26只接受治疗的犬中有23只(88%)存活至出院;中位生存时间为995天。在最后一次随访时,23只存活犬中有15只(65%)仍然存活,8只(35%)因持续性反流相关原因(n = 6)或与GEI无关的原因(2只)死亡。在联系了主人的10只犬中,7只存在持续性反流,通过控制饮食其严重程度有所减轻。与没有这些因素的犬相比,有急性(≤7天)临床症状或先前诊断为巨食管症的犬更有可能出现持续性反流。

结论及临床意义

鉴于出院存活率高和中位生存时间,对于患有GEI的犬应考虑进行治疗。尽管治疗后持续性反流很常见,但通过包括控制饮食和药物治疗在内的医疗管理可能会获得满意的结果。

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