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血流动力学经食管超声心动图对创伤患者急性肾损伤管理及连续性肾脏替代治疗应用的影响

The Impact of Hemodynamic Transesophageal Echocardiography on Acute Kidney Injury Management and Use of Continuous Renal Replacement Therapy in Trauma.

作者信息

Sapp Alex, Drahos Andrew, Lashley Madison, Christie Amy, Christie D Benjamin

出版信息

Am Surg. 2020 Mar 1;86(3):190-194.

PMID:32223796
Abstract

Resuscitation of critically ill trauma patients can be precarious, and errors can cause acute kidney injuries. If renal failure develops, continuous renal replacement therapy (CRRT) may be necessary, but adds expense. Hemodynamic transesophageal echocardiography (hTEE) provides objective data to guide resuscitation. We hypothesized that hTEE use improved acute kidney injury (AKI) management, reserved CRRT use for more severe AKIs, and decreased cost and resource utilization. We retrospectively reviewed 2413 trauma patients admitted to a Level I trauma center's ICU between 2009 and 2015. Twenty-three patients required CRRT before standard hTEE use and 11 required CRRT after; these are the "CRRT" and "CRRT/hTEE" groups, respectively. The hTEE group comprised 83 patients evaluated with hTEE, with AKI managed without CRRT. We compared the average creatinine, change in creatinine, and Acute Kidney Injury Network (AKIN) of "CRRT" with "CRRT/hTEE" and "hTEE." We also analyzed several quality measures including ICU length of stay and cost. "CRRT" had a lower AKIN score (1.6) than "CRRT/hTEE" (2.9) ( = 0.0003). "hTEE" had an AKIN score of 2.1 ( = 0.0387). "CRRT" also had increased ICU days (25.1) compared with "CRRT/hTEE" (20.2) ( = 0.014) and "hTEE" (16.8) ( = 0.003). "CRRT" accrued on average $198,695.81 per patient compared with "CRRT/hTEE" ($167,534.19) and "hTEE" ($53,929.01). hTEE provides valuable information to tailor resuscitation. At our institution, hTEE utilization reserved CRRT for worse AKIs and decreased hospital costs.

摘要

危重症创伤患者的复苏过程可能充满变数,失误可能导致急性肾损伤。如果发展为肾衰竭,可能需要进行持续肾脏替代治疗(CRRT),但这会增加费用。血流动力学经食管超声心动图(hTEE)可提供客观数据以指导复苏。我们假设使用hTEE可改善急性肾损伤(AKI)的管理,将CRRT的使用保留给更严重的AKI,并降低成本和资源利用。我们回顾性分析了2009年至2015年间入住一级创伤中心重症监护病房(ICU)的2413例创伤患者。23例患者在标准hTEE使用前需要CRRT,11例在使用后需要CRRT;这两组分别为“CRRT”组和“CRRT/hTEE”组。hTEE组包括83例接受hTEE评估且AKI未采用CRRT治疗的患者。我们比较了“CRRT”组与“CRRT/hTEE”组和“hTEE”组的平均肌酐、肌酐变化及急性肾损伤网络(AKIN)分级。我们还分析了包括ICU住院时间和费用在内的多项质量指标。“CRRT”组的AKIN评分(1.6)低于“CRRT/hTEE”组(2.9)(P = 0.0003)。“hTEE”组的AKIN评分为2.1(P = 0.0387)。与“CRRT/hTEE”组(20.2天)(P = 0.014)和“hTEE”组(16.8天)(P = 0.003)相比,“CRRT”组的ICU住院天数也更长(25.1天)。“CRRT”组每位患者的平均费用为198,695.81美元,而“CRRT/hTEE”组为167,534.19美元,“hTEE”组为53,929.01美元。hTEE可为调整复苏方案提供有价值的信息。在我们机构,hTEE的应用将CRRT的使用保留给病情更严重的AKI患者,并降低了医院成本。

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The Impact of Hemodynamic Transesophageal Echocardiography on Acute Kidney Injury Management and Use of Continuous Renal Replacement Therapy in Trauma.血流动力学经食管超声心动图对创伤患者急性肾损伤管理及连续性肾脏替代治疗应用的影响
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Utilization of Echocardiography After Acute Kidney Injury Was Associated with Improved Outcomes in Patients in Intensive Care Unit.急性肾损伤后超声心动图的应用与重症监护病房患者预后改善相关。
Int J Gen Med. 2021 Jun 1;14:2205-2213. doi: 10.2147/IJGM.S310445. eCollection 2021.