Institute of Biotechnology, Faculty III - Process Sciences, Technical University of Berlin, Gustav-Meyer-Allee 25, Berlin, 13355, Germany; Department of Agriculture and Food Sciences, Neubrandenburg University of Applied Sciences, Brodaer Str. 2, Neubrandenburg, 17033, Germany; Department of Dermatology, Emory University School of Medicine, 615 Michael St., Atlanta, 30322, Georgia, USA.
Department of Plant Sciences, Microbiology and Biotechnology, Makerere University, P.O Box 7062, Kampala, Uganda.
J Ethnopharmacol. 2020 Jun 28;256:112742. doi: 10.1016/j.jep.2020.112742. Epub 2020 Mar 26.
This study provides the first report on selected traditional medicinal plant use, including parts used and methods of preparation, in the Greater Mpigi region of Uganda. This data supports the conservation of local traditional ecological knowledge and will facilitate future drug discovery research.
Our study aimed to conserve culturally and scientifically-valuable medical knowledge of 16 plant species traditionally used in the Greater Mpigi region in Uganda, namely Albizia coriaria, Cassine buchananii, Combretum molle, Erythrina abyssinica, Ficus saussureana, Harungana madagascariensis, Leucas calostachys, Microgramma lycopodioides, Morella kandtiana, Plectranthus hadiensis, Securidaca longipedunculata, Sesamum calycinum subsp. angustifolium, Solanum aculeastrum, Toddalia asiatica, Warburgia ugandensis and Zanthoxylum chalybeum. An additional objective of the study was an ethnological investigation of the socio-cultural background and medical understanding of diseases treated by traditional healers in the study area.
A pilot survey in the study area revealed that 16 plant species were frequently used in treatment of a variety of medical disorders. In order to obtain more complete information, we conducted a broader ethnobotanical survey using structured interviews with 39 traditional healers from 29 villages, specifically asking about the traditional uses of these 16 medicinal species.
Results of the survey confirmed a high level of traditional use of these species in the Greater Mpigi region. In addition, various other traditional uses and methods of preparation were recorded, most of them for the first time. In total, 75 different medical disorders treated with the plants were documented.
Conservation of traditional knowledge for future generations is vital, as loss has already been recorded due to multiple causes. The need for novel and more effective drugs derived from natural products is more important than ever, making future studies on herbal remedies both justified and urgently required. The traditional healers surveyed in this project also have expectations of the research - they would like to be updated about any resulting studies into the pharmacological efficacy of medicinal plants so that the research findings can inform their confidence in each herbal remedy.
本研究首次报告了乌干达大姆皮吉地区选定的传统药用植物用途，包括使用部位和制备方法。这些数据支持保护当地传统生态知识，并将促进未来的药物发现研究。
我们的研究旨在保护乌干达大姆皮吉地区 16 种传统药用植物的文化和科学价值，这些植物包括 Albizia coriaria、Cassine buchananii、Combretum molle、Erythrina abyssinica、Ficus saussureana、Harungana madagascariensis、Leucas calostachys、Microgramma lycopodioides、Morella kandtiana、Plectranthus hadiensis、Securidaca longipedunculata、Sesamum calycinum subsp. angustifolium、Solanum aculeastrum、Toddalia asiatica、Warburgia ugandensis 和 Zanthoxylum chalybeum。本研究的另一个目的是对研究区域传统治疗师治疗疾病的社会文化背景和医学理解进行民族学调查。
在研究区域进行的初步调查显示，有 16 种植物经常用于治疗各种医疗疾病。为了获得更完整的信息，我们使用结构化访谈对来自 29 个村庄的 39 名传统治疗师进行了更广泛的民族植物学调查，专门询问了这 16 种药用植物的传统用途。
调查结果证实了这些物种在大姆皮吉地区的高传统使用率。此外，还记录了各种其他传统用途和制备方法，其中大多数是首次记录。总共记录了 75 种不同的医疗疾病。
为后代保护传统知识至关重要，因为由于多种原因，传统知识已经流失。对源自天然产物的新型、更有效的药物的需求比以往任何时候都更加重要，因此对草药的未来研究是合理的，也是迫切需要的。本项目调查的传统治疗师也对研究抱有期望——他们希望了解任何有关药用植物药理功效的研究结果，以便他们能够根据研究结果对每种草药的疗效充满信心。
