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嗜碱性粒细胞和肥大细胞上缺乏人类胸腺淋巴细胞抗原(HTLA)。

The absence of a human thymus lymphocyte antigen (HTLA) on bosophils and mast cells.

作者信息

Stallman P J, Van Elven E H, Feltkamp-Vroom T M, Brutel de la Riviĕre A

出版信息

Scand J Immunol. 1977;6(1-2):7-13.

PMID:322262
Abstract

Basophilic granulocytes and mast cells of different species have been reported to originate from thymocytes and other lymphocytes. These observations were recently confirmed when evidence was given that thymic antigen is present on rabbit basophilic granulocytes. In the study reported here, human leukocytes were tested by the immunofluorescence technique and the immunoelectron-microscopy technique to ascertain whether a human thymus lymphocyte antigen (HTLA) could be detected on their surface. We could demonstrate the presence of HTLA on T lymphocytes but not on basophilic granulocytes, nor on mast cells in Cryostat sections of various tissues.

摘要

据报道,不同物种的嗜碱性粒细胞和肥大细胞起源于胸腺细胞和其他淋巴细胞。最近,当有证据表明兔嗜碱性粒细胞上存在胸腺抗原时,这些观察结果得到了证实。在本文报道的研究中,通过免疫荧光技术和免疫电子显微镜技术对人白细胞进行检测,以确定是否能在其表面检测到人类胸腺淋巴细胞抗原(HTLA)。我们能够证实在各种组织的低温切片中,HTLA存在于T淋巴细胞上,但不存在于嗜碱性粒细胞和肥大细胞上。

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