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利用双壁碳纳米管的动态特性检测生物物体

Detection of biological objects using dynamic characteristics of double-walled carbon nanotubes.

作者信息

Patel Ajay M, Joshi Anand Y

机构信息

Mechanical Engineering Department, CHARUSAT University, Changa, Gujarat India.

2Mechatronics Engineering Department, G.H. Patel College of Engineering & Technology, Vallabh Vidyanagar, Gujarat India.

出版信息

Appl Nanosci. 2015;5(6):681-695. doi: 10.1007/s13204-014-0364-8. Epub 2014 Oct 9.

Abstract

This study explores double-walled carbon nanotubes as the sensing devices for biological objects including viruses and bacteria. The biological objects studied include alanine with amino terminal residue, deoxyadenosine with free residue, Coronaviridae and . An expression has been articulated to identify the mass of biological objects from the shift of frequency. Sensitivity of the sensor has been calculated when subjected to such biological objects. Molecular structural mechanics approach has been used for investigating the vibrational responses of zigzag and armchair double-walled carbon nanotube-based nano biosensors. The elastic properties of beam element are calculated by considering mechanical characteristics of covalent bonds between the carbon atoms in the hexagonal lattice. Spring elements are used to describe the interlayer interactions between the inner and outer tubes caused due to the van der Waals forces. The mass of each beam element is assumed as point mass at nodes coinciding with carbon atoms at inner and outer wall of DWCNT. Based on the sensitivity and the frequency shift it can be concluded that cantilever zigzag DWCNTs are better candidates for detecting the biological objects.

摘要

本研究探索了双壁碳纳米管作为用于包括病毒和细菌在内的生物物体的传感装置。所研究的生物物体包括具有氨基末端残基的丙氨酸、具有游离残基的脱氧腺苷、冠状病毒科以及……已阐明一种表达式,用于根据频率偏移识别生物物体的质量。当传感器受到此类生物物体作用时,已计算出其灵敏度。分子结构力学方法已被用于研究基于锯齿形和扶手椅形双壁碳纳米管的纳米生物传感器的振动响应。通过考虑六边形晶格中碳原子之间共价键的力学特性来计算梁单元的弹性特性。弹簧单元用于描述由于范德华力导致的内管和外管之间的层间相互作用。每个梁单元的质量被假定为与双壁碳纳米管内壁和外壁上的碳原子重合的节点处的点质量。基于灵敏度和频率偏移可以得出结论,悬臂锯齿形双壁碳纳米管是检测生物物体的更好候选者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e47/7097327/cba3d5128cc6/13204_2014_364_Article_Fig9_HTML.jpg

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