Gimmel'farb G N, Karimova T Z
Vestn Khir Im I I Grek. 1988 Jun;140(6):123-6.
Surgical correction of the arterial duct and defects of the cardiac septa is followed in the nearest period after surgical correction by lung hypertension which considerably aggravates the postoperative period. The observation of 74 patients has shown that infusions of 1% solution of phosphobion (0.05 mg/kg/min) in the pulmonary artery decrease the pressure in the pulmonary artery, pulmonary-vascular resistance, make the incidence of disturbed heart rate less frequent, reduce the concentration of noradrenaline and prostaglandins.
动脉导管和心脏间隔缺损的外科矫正术后近期会出现肺动脉高压,这会显著加重术后病程。对74例患者的观察表明,在肺动脉内输注1%的磷壁酸溶液(0.05毫克/千克/分钟)可降低肺动脉压力、肺血管阻力,减少心率紊乱的发生率,降低去甲肾上腺素和前列腺素的浓度。