澳大利亚性场所男性中性传播感染和 HIV 的流行情况：观察性研究的系统评价和荟萃分析。

Prevalence of sexually transmissible infections and HIV in men attending sex-on-premises venues in Australia: a systematic review and meta-analysis of observational studies.

机构信息

Clinic 16, 2C Herbert Street, St Leonards, NSW 2065, Australia; and Northern Clinical School, Faculty of Health and Medicine, University of Sydney, Sydney, NSW 2006, Australia; and Corresponding author. Email:

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, Parkville, Vic. 3010, Australia.

出版信息

Sex Health. 2020 Apr;17(2):135-148. doi: 10.1071/SH19150.

DOI:10.1071/SH19150

PMID:32228828

Abstract

UNLABELLED

Background In Australia, men who have sex with men (MSM) have high rates sexually transmissible infections (STIs) and sex-on-premises venue (SOPV) patrons are at risk. This paper assesses Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), syphilis and HIV prevalence in men tested at Australian SOPVs and describes testing services.

METHODS

EMBASE, Medline, PubMed and international conference proceedings were searched for articles reporting on-site SOPV testing between 1 January 2000 and 31 January 2017. Meta-analysis calculated pooled prevalence estimates of STIs by anatomical site.

RESULTS

Twelve cross-sectional studies were identified. Most (8/12) were local sexual health clinics (SHC) outreach services. Participants' mean age was 41.1 years (95% confidence interval (CI) 37.0-43.3; range 17 to 84 years). Testing included CT and NG (9/12), HIV (8/12) and syphilis (5/12). CT and NG prevalence overall summary estimates were 3.4% (95% CI 1.9-5.2%, I2 = 88.7%, P < 0.01) and 1.3% (95% CI 0.7-2.2%, I2 = 75.5%, P < 0.01) respectively. CT and NG prevalence was highest in the ano-rectum and oro-pharynx respectively. The HIV and syphilis pooled estimates were 2.3% (95% CI 1.6-2.9%, I2 = 93.1%, P < 0.01) and 3.2% (95% CI 1.8-4.6%, I2 = 72.8%, P < 0.01) respectively. Participation rate varied.

CONCLUSION

This review examines HIV and STI testing in Australian SOPVs before HIV pre-exposure prophylaxis (PrEP). Findings indicate a high prevalence of STIs. PrEP use and resultant condomless sex may influence STI prevalence. Further research is required to determine the effect of PrEP on the STI prevalence among SOPV patrons.

摘要

未加标签

背景在澳大利亚，男男性行为者（MSM）的性传播感染（STI）发病率较高，性场所（SOPV）顾客也面临风险。本文评估了在澳大利亚 SOPV 接受检测的男性中淋病奈瑟菌（NG）、沙眼衣原体（CT）、梅毒和 HIV 的流行率，并描述了检测服务。

方法

检索 EMBASE、Medline、PubMed 和国际会议论文集，以获取 2000 年 1 月 1 日至 2017 年 1 月 31 日期间现场 SOPV 检测的文章。Meta 分析计算了不同解剖部位 STI 的汇总流行率估计值。

结果

确定了 12 项横断面研究。大多数（8/12）为当地性健康诊所（SHC）外展服务。参与者的平均年龄为 41.1 岁（95%置信区间（CI）37.0-43.3；范围 17 至 84 岁）。检测包括 CT 和 NG（9/12）、HIV（8/12）和梅毒（5/12）。CT 和 NG 的总体汇总估计流行率分别为 3.4%（95%CI 1.9-5.2%，I2=88.7%，P<0.01）和 1.3%（95%CI 0.7-2.2%，I2=75.5%，P<0.01）。CT 和 NG 的流行率在肛门直肠和口腔咽部最高。HIV 和梅毒的汇总估计值分别为 2.3%（95%CI 1.6-2.9%，I2=93.1%，P<0.01）和 3.2%（95%CI 1.8-4.6%，I2=72.8%，P<0.01）。参与率各不相同。