用于检测糖化血红蛋白的分析技术强调了传感器。

Analytical techniques for the detection of glycated haemoglobin underlining the sensors.

机构信息

Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, India.

Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat 131039, India; Centre for Biotechnology, Maharshi Dayanand University, Rohtak 124001, India.

出版信息

Int J Biol Macromol. 2020 Jul 15;155:685-696. doi: 10.1016/j.ijbiomac.2020.03.205. Epub 2020 Mar 27.

DOI:10.1016/j.ijbiomac.2020.03.205

PMID:32229211

Abstract

The increase in concentrations of blood glucose results arise in the proportion of glycated haemoglobin. Therefore, the percentage of glycated haemoglobin in the blood could function as a biomarker for the average glucose level over the past three months and can be used to detect diabetes. The study of glycated haemoglobin tends to be complex as there are about three hundred distinct assay techniques available for evaluating glycated haemoglobin which contributes to some differences in the recorded values from the similar samples. This review outlines distinct analytical methods that have evolved in the recent past for precise recognition of the glycated - proteins.

摘要

血糖浓度的升高会导致糖化血红蛋白的比例增加。因此，血液中的糖化血红蛋白百分比可以作为过去三个月平均血糖水平的生物标志物，并可用于检测糖尿病。糖化血红蛋白的研究往往很复杂，因为目前大约有 300 种不同的检测技术可用于评估糖化血红蛋白，这导致了来自相似样本的记录值存在一些差异。本综述概述了最近出现的用于精确识别糖化蛋白的不同分析方法。