Oder W, Scholz H, Barolin G S
Neurologische Universitätsklinik, Wien.
Wien Med Wochenschr. 1988 Dec 31;138(23-24):604-11.
During a 9-year period an unselected population of 377 patients with clinically suspected viral diseases of the nervous system were hospitalized. Due to the serological findings a definite viral etiology could be established in 123 (33%). With respect to clinical syndromes serological evidence of viral etiology was found in 74% of mono- respectively oligoneuritides, 43% of meningoencephalitides, whereas in polyneuritis only in 18%. Concerning different virus strains varicella zoster virus appears to be largely ahead (65 cases), then come the enterovirus and herpes simplex virus. Clinical features are presented, some exceptional features are discussed. As regards severity of clinical symptoms and course nearly all patients made a good recovery. Only 2 patients died due to complications of the viral infection. In some cases it seems worth noting the association of another virus to a well determined etiology, this occurring simultaneously.
在9年期间,377例临床上疑似患有神经系统病毒性疾病的患者未经挑选就被收治入院。根据血清学检查结果,123例(33%)患者的病毒病因得以明确。就临床综合征而言,在单神经炎或多灶性单神经炎患者中,74%有病毒病因的血清学证据,脑膜脑炎患者中为43%,而在多发性神经炎患者中仅为18%。关于不同病毒株,水痘带状疱疹病毒似乎占主导(65例),其次是肠道病毒和单纯疱疹病毒。文中介绍了临床特征,并讨论了一些特殊情况。至于临床症状的严重程度和病程,几乎所有患者都恢复良好。仅2例患者因病毒感染并发症死亡。在某些情况下,值得注意的是另一种病毒与已明确病因同时存在的关联。