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[遗忘发作]

[Amnestic episodes].

作者信息

Riedmann G, Lindner M, Barolin G S

机构信息

Ludwig-Boltzmann-Institut für Neuro-Rehabilitation und -Prophylaxe, Vorarlberger Landes-Nervenkrankenhauses Valduna, Rankweil.

出版信息

Wien Med Wochenschr. 1988 Dec 31;138(23-24):622-30.

PMID:3222966
Abstract

Amnesic episodes, by no means infrequent occurrences, are likely to trigger off anxiety in the patient and to evade adequate diagnostic interpretation. They consist of an isolated disturbance of short-term memory, manifesting itself as a permanent memory gap. The clinical features may vary from a conspicuous behaviour with stereotype repetition of questions to a completely inconspicuous picture with flawless execution of even highly differentiated behaviour patterns. The vegetative state may either be completely undisturbed or vary from mild impairment with nausea and vertigo to marked vegetative disorder. We are advocating a classification in 3 groups: a) "Genuine" amnesic states as symptoms of impaired blood flow in the basilar system in the absence of other etiological clues. b) "Symptomatic" amnesic episodes with tangible pathogenic factors, such as injury of the head and cervical spine, epilepsy, intoxication with various agents. The "genuine" amnesic states can also be regarded as transitory ischemic attacks of the basilar system. They show the following criteria: preponderance in females beyond middle age, duration of several hours, relatively high frequency of vascular risk factors and degenerative changes in the cervical spine, often triggered off by stress on the cervical spine, low tendency towards recurrence, general clinical benignity. In consequence, we stress the importance of etiological clarification before the onset of therapy. After the diagnosis of "genuine" amnesic state has been established, treatment has to be in accordance with the principles of basilar stroke therapy with subsequent vascular prophylaxis. Nevertheless, because of possible therapeutic or forensic consequences, the "symptomatic" states have to be kept in mind.

摘要

失忆发作绝非罕见,很可能引发患者焦虑,且难以得到充分的诊断性解读。它们表现为短期记忆的孤立性障碍,呈现为永久性记忆缺失。临床特征可能多种多样,从明显的刻板重复提问行为到即使是高度分化的行为模式也能完美执行的完全不明显的表现。自主神经状态可能完全未受干扰,也可能从伴有恶心和眩晕的轻度损害到明显的自主神经紊乱不等。我们主张分为3组:a)“真性”失忆状态,是在没有其他病因线索的情况下基底系统血流受损的症状。b)伴有明确致病因素的“症状性”失忆发作,如头部和颈椎损伤、癫痫、各种药物中毒。“真性”失忆状态也可视为基底系统的短暂性缺血发作。它们具有以下标准:中年以上女性居多,持续数小时,血管危险因素和颈椎退行性变的发生率相对较高,常由颈椎受压引发,复发倾向低,总体临床良性。因此,我们强调在治疗开始前进行病因明确的重要性。在确诊为“真性”失忆状态后,治疗必须遵循基底动脉卒中治疗原则并随后进行血管预防。然而,由于可能的治疗或法医后果,必须牢记“症状性”状态。

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