地塞米松抑制试验、精神分裂症与运动障碍

Dexamethasone suppression test, schizophrenia and movement disorder.

作者信息

Aleem A, Kulkarni A, Yeragani V K

机构信息

Lafayette Clinic, Wayne State University School of Medicine, Detroit, Michigan.

出版信息

Acta Psychiatr Scand. 1988 Dec;78(6):689-94. doi: 10.1111/j.1600-0447.1988.tb06405.x.

DOI:10.1111/j.1600-0447.1988.tb06405.x

PMID:3223326

Abstract

The dexamethasone suppression test (DST) was administered to 20 patients with schizophrenic illness. Ten of these patients also had tardive dyskinesia (TD). The scores on TD and parkinsonism scales were significantly higher in DST nonsuppressors. There was also a significant positive correlation between the post-dexamethasone cortisol level and the movement disorder scales.

摘要

对20例精神分裂症患者进行了地塞米松抑制试验（DST）。其中10例患者还患有迟发性运动障碍（TD）。DST不被抑制者的TD和帕金森症量表评分显著更高。地塞米松后皮质醇水平与运动障碍量表之间也存在显著正相关。