2019 年世界卫生组织（WHO）消化系统肿瘤分类有哪些新变化：神经内分泌肿瘤、阑尾肿瘤和分子检测的部分更新介绍。
What is New in the 2019 World Health Organization (WHO) Classification of Tumors of the Digestive System: Review of Selected Updates on Neuroendocrine Neoplasms, Appendiceal Tumors, and Molecular Testing.
机构信息
Department of Pathology, the Johns Hopkins University, School of Medicine, Baltimore, Maryland.
出版信息
Arch Pathol Lab Med. 2021 Jun 1;145(6):664-677. doi: 10.5858/arpa.2019-0665-RA.
Abstract
CONTEXT.—: The 5th edition of the World Health Organization classification of digestive system tumors discusses several advancements and developments in understanding the etiology, pathogenesis, and diagnosis of several digestive tract tumors.
OBJECTIVE.—: To provide a summary of the updates with a focus on neuroendocrine neoplasms, appendiceal tumors, and the molecular advances in tumors of the digestive system.
DATA SOURCES.—: English literature and personal experiences.
CONCLUSIONS.—: Some of the particularly important updates in the 5th edition are the alterations made in the classification of neuroendocrine neoplasms, understanding of pathogenesis of appendiceal tumors and their precursor lesions, and the expanded role of molecular pathology in establishing an accurate diagnosis or predicting prognosis and response to treatment.
摘要
背景
世界卫生组织第五版消化系统肿瘤分类讨论了在理解几种消化道肿瘤的病因、发病机制和诊断方面的一些进展和发展。
目的
提供更新内容的摘要，重点关注神经内分泌肿瘤、阑尾肿瘤以及消化系统肿瘤的分子进展。
资料来源
英文文献和个人经验。
结论
第五版中特别重要的一些更新包括对神经内分泌肿瘤分类的修改、对阑尾肿瘤及其前体病变发病机制的理解，以及分子病理学在建立准确诊断或预测预后和治疗反应方面的作用扩大。
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What is New in the 2019 World Health Organization (WHO) Classification of Tumors of the Digestive System: Review of Selected Updates on Neuroendocrine Neoplasms, Appendiceal Tumors, and Molecular Testing.2019 年世界卫生组织（WHO）消化系统肿瘤分类有哪些新变化：神经内分泌肿瘤、阑尾肿瘤和分子检测的部分更新介绍。
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