Ulrici V, Händel L, Vogel A, Reissig D
Poliklinik für Prothetische Stomatologie, Karl-Marx-Universität Leipzig, DDR.
Anat Anz. 1988;167(4):329-33.
The influence of artificial unilateral occlusal disturbances on the structure of the temporomandibular joint (TMJ) condyle cartilage was investigated by an experimental study using the miniature pig "MINI-LEWE". After a burden over 20 weeks the side exposed to occlusal disturbance (right TMJ) turned out to have unchanged histological proportions in comparison with control animals. The condyles of the side with pressure loading (left TMJ) exhibited but a changed histological picture. Cartilage resorptions as well as accumulations of large blown chondrocytes indicate an increased tissue reaction within the chondroblastic layer near spongiosa. The morphometric investigations confirm these results. A significant increase was observed in cell density within the chondroblastic layer of the most superior point of the left condylus due to the permanent disturbance of the normal masticatory function.
通过使用“MINI-LEWE”小型猪进行实验研究，探讨了人工单侧咬合干扰对颞下颌关节（TMJ）髁突软骨结构的影响。在超过20周的负荷后，与对照动物相比，暴露于咬合干扰的一侧（右侧TMJ）的组织学比例未发生变化。承受压力负荷一侧（左侧TMJ）的髁突则呈现出改变的组织学图像。软骨吸收以及大的肿胀软骨细胞积聚表明，在靠近海绵体的成软骨细胞层内组织反应增强。形态计量学研究证实了这些结果。由于正常咀嚼功能的长期干扰，左侧髁突最上端的成软骨细胞层内细胞密度显著增加。
