Beauvoir C, Sissman J
Département d'Anesthésie-Réanimation, Hôpital Lapeyronie, Montpellier.
Ann Fr Anesth Reanim. 1988;7(6):511-4. doi: 10.1016/s0750-7658(88)80091-1.
A case is reported of a 56 year old woman admitted for status asthmaticus. She had no known history of cardiovascular disease. During the infusion of salbutamol, there appeared signs of myocardial infarction on the ECG trace. The patient did not complain of any symptoms suggestive of myocardial infarction. Closer cardiac examination and ultrasound revealed features of hypertrophic cardiomyopathy. The first ECG carried out on admission was in fact in favour of this diagnosis. The pathogenesis of this myocardial infarction is discussed: the long lasting hypoxaemia and the tachycardia induced by the salbutamol simulated hard exercise, poorly tolerated by patients suffering from hypertrophic cardiomyopathy. Also, this type of cardiomyopathy is known to be associated with impaired myocardial vasodilator reserve and small vessel coronary artery disease.
报告了一例56岁因哮喘持续状态入院的女性病例。她无已知心血管疾病史。在输注沙丁胺醇期间，心电图显示出心肌梗死的迹象。患者未主诉任何提示心肌梗死的症状。进一步的心脏检查和超声显示为肥厚型心肌病特征。入院时进行的首次心电图实际上支持这一诊断。本文讨论了这种心肌梗死的发病机制：长期低氧血症以及沙丁胺醇诱发的心动过速模拟了剧烈运动，肥厚型心肌病患者对此耐受性差。此外，已知这种类型的心肌病与心肌血管舒张储备受损和小血管冠状动脉疾病有关。
