猪小肠中的颗粒状黏膜淋巴细胞。
Granular mucosal lymphocytes in porcine small intestine.
作者信息
Chu R M, Wang S H, Du Y H
机构信息
Department of Pathology, Pig Research Institute, Taiwan, Chunan, Miaoli, ROC.
出版信息
Am J Vet Res. 1988 Sep;49(9):1456-9.
A subpopulation of purified, interepithelial lymphocytes from porcine small intestinal mucosa contained cytoplasmic granules. Toluidine blue staining revealed metachromatic granules in 13.64% (606/4,450) cells. The cells had scant organelles, a single large nucleus with obvious invagination of the nuclear membrane, and prominent chromatin. Each cell contained 1 to 10 cytoplasmic membrane-bound granules, 0.6 to 1.5 micron in diameter. These findings indicated that the granular mucosal lymphocytes are related morphologically to mucosal mast cells. The presence of serotonin in the granules, confirmed by the serotonin releasing test, provided functional evidence that granular mucosal lymphocytes are related to mucosal mast cells.
从猪小肠黏膜中纯化得到的上皮间淋巴细胞亚群含有细胞质颗粒。甲苯胺蓝染色显示，13.64%（606/4450）的细胞中有异染颗粒。这些细胞细胞器稀少，有一个大的单核，核膜有明显内陷，染色质突出。每个细胞含有1至10个直径为0.6至1.5微米的细胞质膜结合颗粒。这些发现表明，颗粒状黏膜淋巴细胞在形态上与黏膜肥大细胞有关。血清素释放试验证实颗粒中存在血清素，这为颗粒状黏膜淋巴细胞与黏膜肥大细胞有关提供了功能证据。
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