Department of Pharmacotherapy & Outcomes Science, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA.
Center for Pharmacy Practice Innovation, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA.
J Hum Hypertens. 2020 Jul;34(7):487-494. doi: 10.1038/s41371-020-0331-7. Epub 2020 Apr 1.
Hypertension (HTN) is a leading cause of death and disability throughout the world. Yet, despite widely available treatment options, blood pressure (BP) control rates have remained relatively stagnant. One approach to address this issue is through collaborative care models, particularly those employing pharmacists. Numerous randomized controlled trials (RCT) have demonstrated the effectiveness of pharmacist interventions to improve BP control across primary care, community-based, and telemedicine models. A meta-analysis of 39 RCTs has demonstrated that pharmacist interventions significantly reduce both systolic and diastolic BP compared with controls across diverse patient populations. Pharmacists can contribute to HTN management in a variety of ways, including assisting with out-of-office monitoring, providing education, identifying and resolving nonadherence, and titrating antihypertensive therapy to achieve BP control. In this review, we discuss key trials conducted in recent years that support the role of pharmacists in HTN management and provide guidance on practical considerations for working collaboratively with pharmacists to improve BP control.
高血压（HTN）是全世界导致死亡和残疾的主要原因之一。尽管有广泛的治疗选择，但血压（BP）控制率仍然相对停滞不前。解决这个问题的一种方法是通过协作式护理模式，特别是那些采用药剂师的模式。许多随机对照试验（RCT）已经证明了药剂师干预在改善基层医疗、社区和远程医疗模式下的血压控制方面的有效性。对 39 项 RCT 的荟萃分析表明，与对照组相比，药剂师干预可显著降低不同患者人群的收缩压和舒张压。药剂师可以通过多种方式为高血压管理做出贡献，包括协助进行非诊室监测、提供教育、识别和解决不依从性以及调整抗高血压治疗以控制血压。在这篇综述中，我们讨论了近年来进行的支持药剂师在高血压管理中的作用的关键试验，并就与药剂师合作以改善血压控制的实际考虑因素提供了指导。
