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与婴儿血管瘤相关的鉴别诊断困难——病例报告及文献综述

Differential diagnosis difficulties related to infantile hemangioma - case report and literature review.

作者信息

Ţarcă Elena, Cojocaru Elena, Roşu Solange Tamara, Butnariu Lăcrămioara Ionela, Plămădeală Petru, Moisă Ştefana Maria

机构信息

Department of Morphofunctional Sciences - Pathology, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania;

出版信息

Rom J Morphol Embryol. 2019;60(4):1375-1379.

Abstract

Infantile hemangioma is a benign vascular tumor that is often present in the cephalic region and can grow rapidly in size, causing serious complications. The hemangioma with oro-maxillofacial sphere localization may often pose differential diagnosis problems, requiring additional investigations. We present the case of a 3-month-old baby who was brought to the Emergency Room for acute respiratory failure and dysphagia caused by the rapid increase in size of a soft palate and lateral pharyngeal wall tumor. The clinical examination revealed a "wine stain" hemangioma in the inter-eyebrow and frontal areas, a hemangioma in the right genial area, 1∕1.5 cm in diameter, growing rather in depth than on the surface, and a purplish-blue tumoral mass with irregular edges, grown in the soft palate and in the right lateral wall of the pharynx, which impaired both eating and breathing. Obstructive phenomena have been aggravated by an acute respiratory infection. Due to the inconsistencies between different medical specialties about the nature of the tumor and the suspicion of malignancy, in order to establish the correct diagnosis and therapeutic management, urgent tumor biopsy was required. After starting oral treatment with Propranolol, the evolution was favorable. Infantile hemangiomas may sometimes be hard to diagnose, requiring additional imaging examinations, and sometimes-pathological examination. Since it may affect a vital function, or the patient's esthetic appearance, or if the tumor has ulcerated, bleeds or got infected, the certain diagnosis and the onset of treatment should be done as soon as possible.

摘要

婴儿血管瘤是一种良性血管肿瘤,常出现在头面部区域,且体积可能迅速增大,引发严重并发症。位于口腔颌面区域的血管瘤常常会带来鉴别诊断问题,需要进一步检查。我们报告一例3个月大婴儿的病例,该婴儿因软腭及咽侧壁肿瘤体积迅速增大导致急性呼吸衰竭和吞咽困难而被送往急诊室。临床检查发现,患儿眉间及额部有“葡萄酒色斑”血管瘤,右颏部有一个直径1∕1.5厘米的血管瘤,其生长方向是向深部而非表面,软腭及右侧咽壁有一个边缘不规则的紫蓝色肿瘤团块,影响了进食和呼吸。急性呼吸道感染加重了梗阻现象。由于不同医学专科对肿瘤性质存在分歧且怀疑有恶性可能,为明确正确诊断和治疗方案,需紧急进行肿瘤活检。开始口服普萘洛尔治疗后,病情好转。婴儿血管瘤有时可能难以诊断,需要进行额外的影像学检查,有时还需要病理检查。由于其可能影响重要功能、患者美观,或者肿瘤发生溃疡、出血或感染,应尽快明确诊断并开始治疗。

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