Nishimiya J
Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
No To Shinkei. 1988 Jun;40(6):585-91.
The author studied the incidence of computed tomographic evidences of cerebellar atrophy in 2,102 neurologically normal subjects. The subjects were selected from approximately 10,000 cases who underwent CT examination at Juntendo University hospital since April 17, 1978 to October 30, 1979. The 2,102 subjects were classified into 10 groups according to their age, as following: 1) below the age of 1 year, 2) between 1 and 4 years, 3) between 5 and 9 years, 4) second decade, 5) third decade, 6) fourth decade, 7) fifth decade, 8) sixth decade, 9) seventh decade, 10) after the age of seventy. The incidence of enlarged cerebellar vermis fissures, cerebellar hemispheric fissures, subarachnoid space around the cerebellum and the fourth ventricle were explored on CT. As regards the fourth ventricle, the maximum transverse width of the fourth ventricle and the maximum inside diameter of the posterior fossa were measured on CT, and ratio of the width of the fourth ventricle against the diameter of the posterior fossa were calculated. Statistical analysis was performed using chi 2 test or t test in each age group. The results obtained were as following: I. The incidence of enlarged cerebellar vermis fissures and cerebellar hemispheric fissures increased gradually with aging. Though the difference were almost significant in any groups older than 20 years. It was noteworthy among those who were older than 60 years. II. The incidence of enlarged subarachnoid space around the cerebellum also increased significantly after the age of sixty, III. In subjects older than twenty, the width of the fourth ventricle increased with aging.(ABSTRACT TRUNCATED AT 250 WORDS)
作者研究了2102名神经系统正常受试者的小脑萎缩的计算机断层扫描证据的发生率。这些受试者选自1978年4月17日至1979年10月30日在顺天堂大学医院接受CT检查的约10000例病例。根据年龄,将这2102名受试者分为10组,如下:1)1岁以下;2)1至4岁;3)5至9岁;4)第二个十年;5)第三个十年;6)第四个十年;7)第五个十年;8)第六个十年;9)第七个十年;10)70岁以后。在CT上观察小脑蚓部裂、小脑半球裂、小脑周围蛛网膜下腔和第四脑室扩大的发生率。关于第四脑室,在CT上测量第四脑室的最大横径和后颅窝的最大内径,并计算第四脑室宽度与后颅窝直径的比值。在每个年龄组中使用卡方检验或t检验进行统计分析。获得的结果如下:I.小脑蚓部裂和小脑半球裂扩大的发生率随年龄增长逐渐增加。尽管在任何20岁以上的组中差异几乎都具有统计学意义。在60岁以上的人群中这一点值得注意。II.小脑周围蛛网膜下腔扩大的发生率在60岁以后也显著增加。III.在20岁以上的受试者中,第四脑室的宽度随年龄增长而增加。(摘要截断于250字)