Amity Institute of Information Technology, Amity University Uttar Pradesh, Noida, India.
Thapar Institute of Engineering and Technology, Patiala, India.
Int J Neurosci. 2021 Jun;131(6):555-570. doi: 10.1080/00207454.2020.1750390. Epub 2020 Apr 15.
The brain tumor grows inside the skull and interposes with regular brain functioning. The tumor growth may possibly result in cancer at a later stage. The early detection of brain tumor is crucial for successful treatment of fatal disease. The tumor presence is normally detected by Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) images. The MRI/CT images are highly complex and involve huge data. This requires highly tedious and time-consuming process for detection of small tumors for the neurologists. Thus, there is a need to develop an effective and less time-consuming imaging technique for early detection of brain tumors.
This paper mainly focuses on early detecting and localizing the brain tumor region using segmentation of patient's MRI images. The Matlab software experiments are performed on a set of fifteen tumorous MRI images. In the proposed work, four image segmentation modalities namely watershed transform, k-means clustering, thresholding and Fuzzy C Means Clustering techniques with median filtering have been implemented.
The results are verified by quantitative comparison of results in terms of image quality evaluation parameters-Entropy, standard deviation and Naturalness Image Quality Evaluator. A remarkable rise in the entropy and standard deviation values has been noticed.
The watershed transform segmentation with median filtering yields the best quality brain tumor images. The noteworthy improvement in visibility of the MRI images may highly increase the possibilities of early detection and successful treatment of brain tumor disease and thereby assists the clinicians to decide the precise therapies.
脑肿瘤在颅骨内生长,干扰正常的大脑功能。肿瘤生长可能导致癌症在后期发生。早期发现脑肿瘤对于致命疾病的成功治疗至关重要。肿瘤的存在通常通过计算机断层扫描 (CT) 或磁共振成像 (MRI) 图像来检测。MRI/CT 图像非常复杂,涉及大量数据。这需要神经科医生进行高度繁琐和耗时的过程来检测小肿瘤。因此,需要开发一种有效的、耗时更少的成像技术,以便早期发现脑肿瘤。
本文主要关注使用患者 MRI 图像的分割来早期检测和定位脑肿瘤区域。在一组十五个肿瘤 MRI 图像上进行了 Matlab 软件实验。在提出的工作中,实现了四种图像分割方式,即分水岭变换、k-均值聚类、阈值处理和带中值滤波的模糊 C 均值聚类技术。
通过图像质量评估参数-熵、标准差和自然图像质量评估器的定量比较来验证结果。注意到熵和标准差值显著增加。
带中值滤波的分水岭变换分割产生了质量最好的脑肿瘤图像。MRI 图像的可见度有了显著提高,这可能极大地增加了早期发现和成功治疗脑肿瘤疾病的可能性,并帮助临床医生决定更精确的治疗方案。