Department of Neurology, SMDZ in Zabrze, Medical University of Silesia in Katowice, Zabrze, Poland.
Department of Neurology with Stroke Subunit, Provincial Specialist Hospital, Bytom, Poland.
Neurol Res. 2020 Jun;42(6):471-476. doi: 10.1080/01616412.2020.1746508. Epub 2020 Apr 2.
: Cardioembolic stroke accounts for approximately 15-25% of ischemic strokes and is characterized by a poor prognosis. Atrial fibrillation (AF) is more commonly diagnosed in the elderly.The aim of the study was the assessment of the manifestations of AF in patients hospitalized due to cerebral stroke, with particular attention paid to newly diagnosed AF.: A retrospective analysis was performed on 998 cerebral stroke patients. The data were analyzed for sex, age, cerebral stroke risk factors, drugs, NIHSS, RANKIN scores and ECG recordings on admission and at discharge.: The mean age of disease onset was 73 ± 16 years. Women accounted for 50.8% of patients. AF prior to hospital admission was diagnosed in 20.1% of patients, while AF in 26.3% of patients during hospitalization. Hypercholesterolemia, hypertriglyceridemia and smoking were more commonly reported in ischemic stroke patients without AF compared to patients with ischemic stroke and AF. Ischemic heart disease, more frequent deaths, and a worse prognosis were more frequently observed in patients with ischemic stroke and AF compared to patients without AF. The first manifestation of AF in 25% of stroke patients was related to the period of the first 10 days of hospitalization.: The above data should prompt neurologists, cardiologists and family doctors to try to detect AF as a risk factor for ischemic stroke which worsens patient prognosis, prolongs hospital stay and contributes to increase in mortality, especially when more effective drug treatment is currently possible.
心源性脑卒占缺血性脑卒中的 15-25%,其预后较差。心房颤动(AF)在老年人中更为常见。本研究旨在评估因脑卒住院患者的 AF 表现,特别关注新诊断的 AF。
对 998 例脑卒患者进行回顾性分析。分析性别、年龄、脑卒危险因素、药物、NIHSS、RANKIN 评分和入院及出院时的心电图记录。
发病时的平均年龄为 73±16 岁。女性占患者的 50.8%。入院前诊断为 AF 的患者占 20.1%,而住院期间诊断为 AF 的患者占 26.3%。与无 AF 的缺血性卒患者相比,有 AF 的缺血性卒患者更常报告高胆固醇血症、高三酰甘油血症和吸烟。与无 AF 的患者相比,有 AF 的缺血性卒患者更常出现缺血性心脏病、更频繁的死亡和预后更差。25%的卒患者的 AF 首次表现与住院的前 10 天期间有关。
上述数据应促使神经科医生、心脏病专家和家庭医生尝试检测 AF 作为缺血性卒的危险因素,这会使患者的预后恶化、延长住院时间并导致死亡率增加,特别是在目前可能进行更有效的药物治疗时。