Paediatric Nephrology, Great Ormond Street Hospital For Children NHS Foundation Trust, London, UK
Great Ormond Street Institute of Child Health, University College London, London, UK.
Arch Dis Child. 2021 Apr;106(4):384-386. doi: 10.1136/archdischild-2019-318272. Epub 2020 Apr 2.
To investigate access to paediatric renal transplantation and examine potential barriers within the process.
Cross-sectional, multicentre, observational study where paediatric nephrology centres in the UK were requested to provide data on transplantation plans for all children (<18 years) with end-stage kidney disease (ESKD).
308 children with ESKD were included in this study from 12 out of 13 UK paediatric nephrology centres. 139 (45%) were being prepared for living donor transplantation and 82 (27%) were listed for deceased donor transplantation. The most common cited factors delaying transplantation from occurring in children were disease factors (36%), donor availability (27%) and size of the child (20%). Psychosocial factors were listed as a barrier in 19% of children.
In this study we have documented the main barriers to renal transplantation in children. Some identified factors may be modifiable through local or national intervention, including donor availability and patient psychosocial factors.
调查儿科肾移植的可及性，并检查该过程中的潜在障碍。
这是一项横断面、多中心、观察性研究，要求英国的儿科肾脏病中心提供所有终末期肾病（ESKD）儿童（<18 岁）的移植计划数据。
本研究纳入了来自英国 13 个儿科肾脏病中心中的 12 个中心的 308 名 ESKD 儿童。139 名（45%）正在准备活体供者移植，82 名（27%）已列入已故供者移植名单。导致儿童移植延迟的最常见因素是疾病因素（36%）、供者可用性（27%）和儿童体型（20%）。19%的儿童认为心理社会因素是一个障碍。
在这项研究中，我们记录了儿童肾移植的主要障碍。一些确定的因素可能可以通过局部或国家干预来改变，包括供者的可用性和患者的心理社会因素。
