内分泌和代谢与冠状病毒感染的关联。
Endocrine and metabolic link to coronavirus infection.
机构信息
Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany.
Department of Diabetes, School of Life Course Science & Medicine, King's College London, London, UK.
出版信息
Nat Rev Endocrinol. 2020 Jun;16(6):297-298. doi: 10.1038/s41574-020-0353-9.
Abstract
Type 2 diabetes mellitus and hypertension are the most common comorbidities in patients with coronavirus infections. Emerging evidence demonstrates an important direct metabolic and endocrine mechanistic link to the viral disease process. Clinicians need to ensure early and thorough metabolic control for all patients affected by COVID-19.
摘要
2 型糖尿病和高血压是冠状病毒感染患者最常见的合并症。新出现的证据表明，病毒发病机制与重要的直接代谢和内分泌机制有关。临床医生需要确保所有 COVID-19 患者的代谢得到早期和彻底的控制。
相似文献
1
Endocrine and metabolic link to coronavirus infection.内分泌和代谢与冠状病毒感染的关联。
Nat Rev Endocrinol. 2020 Jun;16(6):297-298. doi: 10.1038/s41574-020-0353-9.
2
Use of pioglitazone in people with type 2 diabetes mellitus with coronavirus disease 2019 (COVID-19): Boon or bane?在2型糖尿病合并2019冠状病毒病（COVID-19）患者中使用吡格列酮：是福是祸？
Diabetes Metab Syndr. 2020 Sep-Oct;14(5):829-831. doi: 10.1016/j.dsx.2020.06.015. Epub 2020 Jun 10.
3
Very low reporting rate of connective tissue diseases among coronavirus disease 2019 (Covid-19) patients and the renin-angiotensin system - An overlooked association?2019冠状病毒病（Covid-19）患者中结缔组织病的报告率极低与肾素-血管紧张素系统——一种被忽视的关联？
Eur J Intern Med. 2020 Oct;80:106-107. doi: 10.1016/j.ejim.2020.06.012. Epub 2020 Jun 12.
4
COVID-19 challenging cell biology.新冠病毒对细胞生物学构成挑战。
Protoplasma. 2020 May;257(3):619-620. doi: 10.1007/s00709-020-01506-z. Epub 2020 Apr 24.
5
Central involvement of SARS-CoV-2 may aggravate ARDS and hypertension.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的中枢神经系统受累可能会加重急性呼吸窘迫综合征（ARDS）和高血压。
J Renin Angiotensin Aldosterone Syst. 2020 Oct-Dec;21(4):1470320320972015. doi: 10.1177/1470320320972015.
6
COVID-19, Renin-Angiotensin System, and Hematopoiesis.新型冠状病毒肺炎、肾素-血管紧张素系统与造血作用
Turk J Haematol. 2020 Aug 28;37(3):207-208. doi: 10.4274/tjh.galenos.2020.2020.0174. Epub 2020 May 12.
7
Why are women better protected from COVID-19: Clues for men? Sex and COVID-19.为何女性在新冠病毒肺炎中受到更好的保护：对男性的启示？性别与新冠病毒肺炎。
Int J Cardiol. 2020 Sep 15;315:105-106. doi: 10.1016/j.ijcard.2020.05.026. Epub 2020 May 11.
8
COVID-19 Interference with Renin-Angiotensin System in the Context of Heart Failure.心力衰竭背景下COVID-19对肾素-血管紧张素系统的干扰
mBio. 2020 May 22;11(3):e00946-20. doi: 10.1128/mBio.00946-20.
9
COVID-19 Pandemic: Hopes from Proteomics and Multiomics Research.COVID-19 大流行：蛋白质组学和多组学研究的希望。
OMICS. 2020 Aug;24(8):457-459. doi: 10.1089/omi.2020.0073. Epub 2020 May 18.
10
ACE2 receptor expression in testes: implications in coronavirus disease 2019 pathogenesis†.睾丸中 ACE2 受体的表达：在 2019 年冠状病毒病发病机制中的意义。
Biol Reprod. 2020 Aug 21;103(3):449-451. doi: 10.1093/biolre/ioaa080.
引用本文的文献
1
Factors affecting COVID-19 outcomes in Ireland: findings from a national database of 1,408,249 cases diagnosed between 2020 and 2022.影响爱尔兰新冠疫情结果的因素：来自2020年至2022年期间确诊的1,408,249例病例的国家数据库的研究结果
BMC Public Health. 2025 Aug 21;25(1):2877. doi: 10.1186/s12889-025-24057-5.
2
Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.肥胖对非人灵长类动物感染SARS-CoV-2的急性反应及新冠病毒感染后急性后遗症（PASC）发展的影响。
PLoS Pathog. 2025 Jul 24;21(7):e1012988. doi: 10.1371/journal.ppat.1012988. eCollection 2025 Jul.
3
Abnormalities of Endocrine Function Tests in COVID-19-Recovered Individuals.新冠康复者内分泌功能测试异常
Indian J Endocrinol Metab. 2025 May-Jun;29(3):325-331. doi: 10.4103/ijem.ijem_32_25. Epub 2025 Jun 28.
4
Role of Galanin system and insulin resistance parameters as predictive tools for diagnosis of Long-COVID patients.甘丙肽系统和胰岛素抵抗参数作为预测工具在长新冠患者诊断中的作用。
Biochem Biophys Rep. 2025 Jun 3;43:102068. doi: 10.1016/j.bbrep.2025.102068. eCollection 2025 Sep.
5
Understanding the interplay between COVID-19 and diabetes: insights for the post-pandemic era.了解2019冠状病毒病与糖尿病之间的相互作用：大流行后时代的见解。
Front Endocrinol (Lausanne). 2025 May 21;16:1599969. doi: 10.3389/fendo.2025.1599969. eCollection 2025.
6
Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.肥胖对非人灵长类动物感染SARS-CoV-2的急性反应及新冠病毒感染后急性后遗症（PASC）发展的影响。
bioRxiv. 2025 Feb 22:2025.02.18.638792. doi: 10.1101/2025.02.18.638792.
7
Growth hormone replacement therapy enhances humoral response to COVID-19 mRNA vaccination in patients with adult-onset growth hormone deficiency.生长激素替代疗法可增强成年起病的生长激素缺乏患者对新冠病毒mRNA疫苗的体液免疫反应。
J Endocrinol Invest. 2025 May;48(5):1283-1288. doi: 10.1007/s40618-024-02528-7. Epub 2025 Feb 3.
8
Endocrine dysregulation in COVID-19: molecular mechanisms and insights.新型冠状病毒肺炎中的内分泌失调：分子机制与研究进展。
Front Endocrinol (Lausanne). 2024 Oct 22;15:1459724. doi: 10.3389/fendo.2024.1459724. eCollection 2024.
9
Metabolic reprogramming tips vaccinia virus infection outcomes by stabilizing interferon-γ induced IRF1.代谢重编程通过稳定干扰素-γ诱导的 IRF1 来影响痘病毒感染的结果。
PLoS Pathog. 2024 Oct 30;20(10):e1012673. doi: 10.1371/journal.ppat.1012673. eCollection 2024 Oct.
10
NEW-ONSET PRIMARY ADRENAL INSUFFICIENCY AFTER COVID-19: CASE REPORT.新冠病毒感染后新发原发性肾上腺皮质功能减退症：病例报告
Acta Endocrinol (Buchar). 2024 Jan-Mar;20(1):90-92. doi: 10.4183/aeb.2024.90. Epub 2024 Oct 3.
本文引用的文献
1
Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.结构基础为单域骆驼科抗体对β冠状病毒的强效中和作用。
Cell. 2020 May 28;181(5):1004-1015.e15. doi: 10.1016/j.cell.2020.04.031. Epub 2020 May 5.
2
The burden of allergic diseases in the Indian subcontinent: barriers and challenges.印度次大陆过敏性疾病的负担：障碍与挑战。
Lancet Glob Health. 2020 Apr;8(4):e478-e479. doi: 10.1016/S2214-109X(20)30061-9.
Zotero 插件