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中国香港地区老年高血压患者的健康相关生活质量及使用 EQ-5D-5L 评估其最小重要差异。

Health-related quality of life in elderly people with hypertension and the estimation of minimally important difference using EQ-5D-5L in Hong Kong SAR, China.

机构信息

The Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China.

出版信息

Eur J Health Econ. 2020 Aug;21(6):869-879. doi: 10.1007/s10198-020-01178-9. Epub 2020 Apr 2.

Abstract

OBJECTIVE

This study examined health-related quality of life (HRQoL) in elderly patients with hypertension in Hong Kong (HK) by using EQ-5D-5L and estimated the minimally important difference (MID) of the EQ-5D-5L index score for this population.

METHOD

We analysed secondary data from a population-based cross-sectional patient experience survey in HK. The EQ-5D-5L HK version was used to assess patients' HRQoL. The mean EQ-5D index scores for different subgroups were evaluated by ANOVA. Tobit regression models were used to investigate the relationship between hypertension and HRQoL. An instrument-defined approach was adopted to estimate the MID of the EQ-5D-5L index score.

RESULT

A total of 3,351 patients' records met the selection criteria and were used in this study for our analysis. The mean age was 72.74 years, and 54.97% of respondents were female. The mean EQ-5D index score was 0.83. Most of the respondents (83.36%) reported having no problem with self-care. The Tobit regression model indicated that an increasing number of chronic conditions co-morbidity with hypertension contribute to a decrease in the EQ-5D index score. The overall MID estimate of the EQ-5D index score was 0.0917 and the adjusted MID was 0.0715. The MID estimates varied among respondents of different sexes and ages.

CONCLUSION

The HRQoL and MID estimate of EQ-5D for elderly individuals with hypertension was reported, which provide valuable information for assisting health-care professionals in making clinical decisions in hypertensive care.

摘要

目的

本研究通过使用 EQ-5D-5L 评估香港(HK)老年高血压患者的健康相关生活质量(HRQoL),并估计该人群 EQ-5D-5L 指数得分的最小重要差异(MID)。

方法

我们分析了 HK 一项基于人群的横断面患者体验调查的二级数据。使用 EQ-5D-5L HK 版本评估患者的 HRQoL。通过方差分析评估不同亚组的平均 EQ-5D 指数得分。采用 Tobit 回归模型探讨高血压与 HRQoL 之间的关系。采用仪器定义方法估计 EQ-5D-5L 指数得分的 MID。

结果

共有 3351 名患者的记录符合选择标准,用于本研究的分析。平均年龄为 72.74 岁,54.97%的受访者为女性。平均 EQ-5D 指数得分为 0.83。大多数受访者(83.36%)报告在自我护理方面没有问题。Tobit 回归模型表明,高血压合并的慢性疾病数量增加会导致 EQ-5D 指数得分下降。EQ-5D 指数得分的总体 MID 估计值为 0.0917,调整后的 MID 为 0.0715。MID 估计值在不同性别和年龄的受访者中有所不同。

结论

报告了 EQ-5D 用于评估老年高血压患者的 HRQoL 和 MID 估计值,为高血压护理中协助医疗保健专业人员做出临床决策提供了有价值的信息。

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