成年公牛体内某种线虫引起的脑脊线虫病。
Cerebrospinal nematodosis caused by species in an adult bull.
作者信息
MacKay Evelyn E, Fratzke Alycia P, Gerhold Richard W, Porter Brian F, Washburn Kevin E
机构信息
Departments of Large Animal Clinical Sciences (MacKay, Washburn) and Veterinary Pathobiology (Fratzke, Porter), College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX.
Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN (Gerhold).
出版信息
J Vet Diagn Invest. 2020 May;32(3):486-489. doi: 10.1177/1040638720915530. Epub 2020 Apr 3.
A 2-y-old Brahman bull was presented with progressive hindlimb ataxia and paraparesis that led to recumbency. Postmortem examination revealed scattered pinpoint, red-brown foci within the brainstem and gray matter of the spinal cord, and a larger lesion within the spinal cord at the level of T13. Histology of the section of T13 contained cross-sections of nematodes consistent with . Evidence of inflammation was present in other affected areas of the spinal cord and brain. DNA extraction and nested PCR were performed, which demonstrated 98% identity and 100% coverage to both and . Our case highlights the utility of DNA sequencing in parasite identification.
一头2岁的婆罗门公牛出现进行性后肢共济失调和轻瘫，最终导致卧地不起。尸检发现脑干和脊髓灰质内有散在的针尖大小的红棕色病灶，T13水平的脊髓内有一个较大的病变。T13切片的组织学检查发现含有与[寄生虫名称未给出]一致的线虫横切面。在脊髓和脑的其他受影响区域存在炎症证据。进行了DNA提取和巢式PCR，结果显示与[寄生虫名称未给出]的同一性为98%，覆盖率为100%。我们的病例突出了DNA测序在寄生虫鉴定中的实用性。
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