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一匹患有颈椎侧弯和脊髓脊膜炎的马的细颈囊尾蚴脑脊髓线虫病

Parelaphostrongylus tenuis Cerebrospinal Nematodiasis in a Horse with Cervical Scoliosis and Meningomyelitis.

作者信息

Mittelman N S, Divers T J, Engiles J B, Gerhold R, Ness S, Scrivani P V, Southard T, Johnson A L

机构信息

New Bolton Center at the University of Pennsylvania School of Veterinary Medicine Kennett Square, PA.

Cornell University College of Veterinary Medicine Equine and Farm Animal Hospital, Ithaca, NY.

出版信息

J Vet Intern Med. 2017 May;31(3):890-893. doi: 10.1111/jvim.14691. Epub 2017 Mar 20.

Abstract

There are reports of horses with acute onset acquired cervical scoliosis and cutaneous analgesia. The underlying dorsal gray column myelitis that produces these neurologic signs has been only presumptively attributed to migration of Parelaphostrongylus tenuis within the spinal cord. Despite previous confirmation brain by polymerase chain reaction testing, of P. tenuis within the brain of horses by polymerase chain reaction testing, genetic testing has failed to definitively identify the presence of this parasite in cases of equine myelitis. This case report provides molecular confirmation via polymerase chain reaction of P. tenuis within the cervical spinal cord of a horse with scoliosis and cutaneous analgesia.

摘要

有关于马匹急性发作获得性颈椎侧弯和皮肤感觉缺失的报道。产生这些神经症状的潜在背侧灰质柱脊髓炎仅被推测归因于细颈囊尾蚴在脊髓内的迁移。尽管此前通过聚合酶链反应检测已在马的大脑中证实存在细颈囊尾蚴,但基因检测未能在马脊髓炎病例中明确鉴定出这种寄生虫的存在。本病例报告通过聚合酶链反应提供了分子学证据,证实一匹患有脊柱侧弯和皮肤感觉缺失的马的颈脊髓内存在细颈囊尾蚴。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a92/5435076/05b081b877cb/JVIM-31-890-g001.jpg

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