Zasieda Yu, Solomianyi R
1"Man's Health" Clinic, Kiev; 2Zaporozhye State Medical University, Ukraine.
1"Man's Health" Clinic, Kiev, Ukraine.
Georgian Med News. 2020 Feb(299):29-33.
Chronic inflammatory diseases of the prostate are one of the most common andurological nosology. This group of diseases includes heterogeneous pathology such as chronic bacterial prostatitis, chronic non-infectious prostatitis, prostate asymptomatic inflammation and chronic pelvic pain syndrome. Currently, biological and physiotherapeutic chronic prostate inflammatory diseases treatment methods are actively being studied, such as platelet rich plasma (PRP) therapy and low-intensity pulsed ultrasound (LIPUS) therapy. Aim - assessment of the efficacy of the treatment model of chronic nonspecific bacterial prostatitis which includes combined application of transurethral vacuum drainage with PRP electrophonophoresis and transrectal LIPUS of prostate gland. A prospective clinical study was conducted on a contingent of 50 patients of "Men's Health Clinic" (Kiev, Ukraine) suffering from chronic nonspecific bacterial prostatitis (ICD-10: N41.1). LIPUS and PRP combination demonstrates the further progress of the therapeutic effect in terms of difficulty urinating (p=0,04) and a subjective decrease of life quality (p≤0,01). Overall I-PSS score indicates a decrease in the overall severity to a mild level (p≤0,01). VAS level of pelvic pain shoved the significant clinical effect of LIPUS and PRP combination (p≤0,01). LIPUS and PRP combination showed efficacy in reduction of leucocytes in ejaculate (p≤0,01), normalization of semen acidity (p≤0,01) and mucus production (p≤0,01). Treatment model of chronic nonspecific bacterial prostatitis which includes combined application of transurethral vacuum drainage with PRP electrophonophoresis and transrectal LIPUS as an addition to standard antibiotic therapy had shown deep positive impact on prostate inflammation. Effects of PRP and LIPUS combined application are additive to effects of traditional interventions in general results of therapy, life quality, pain reduction and normalization of ejaculate parameters of patients with chronic prostate inflammation.
前列腺慢性炎症性疾病是最常见的泌尿系统疾病之一。这类疾病包括多种不同的病理情况，如慢性细菌性前列腺炎、慢性非感染性前列腺炎、前列腺无症状性炎症和慢性盆腔疼痛综合征。目前，生物和物理治疗慢性前列腺炎症性疾病的方法正在积极研究中，如富血小板血浆（PRP）疗法和低强度脉冲超声（LIPUS）疗法。目的——评估慢性非特异性细菌性前列腺炎治疗模式的疗效，该模式包括经尿道真空引流联合PRP电离子透入疗法及经直肠前列腺LIPUS治疗。对乌克兰基辅“男性健康诊所”的50例患有慢性非特异性细菌性前列腺炎（国际疾病分类第十版：N41.1）的患者进行了一项前瞻性临床研究。LIPUS与PRP联合应用在排尿困难方面（p = 0.04）以及生活质量主观下降方面（p≤0.01）显示出治疗效果的进一步改善。总体国际前列腺症状评分（I-PSS）表明总体严重程度降至轻度水平（p≤0.01）。盆腔疼痛视觉模拟评分（VAS）显示LIPUS与PRP联合应用具有显著的临床效果（p≤0.01）。LIPUS与PRP联合应用在降低精液白细胞方面（p≤0.01）、精液酸度正常化方面（p≤0.01）以及黏液分泌方面（p≤0.01）均显示出疗效。慢性非特异性细菌性前列腺炎的治疗模式，包括经尿道真空引流联合PRP电离子透入疗法及经直肠LIPUS，并作为标准抗生素治疗的补充，已显示出对前列腺炎症有深远的积极影响。在慢性前列腺炎患者的治疗总体结果、生活质量、疼痛减轻以及精液参数正常化方面，PRP和LIPUS联合应用的效果是传统干预措施效果的累加。
