Marchetti C, Poggi P, Calligaro A, Arbustini E
Istituto di Istologia ed Embriologia Generale, Università di Pavia, Italia.
J Submicrosc Cytol Pathol. 1988 Oct;20(4):701-8.
Lymph capillary features have been investigated in human hearts from subjects affected by dilated cardiomyopathy. The edematous myocardial regions present dilated lymph capillaries with a slightly indented endothelial wall. The intercellular adhesions are not especially intricate; the open junctions between contiguous endothelial cells are more numerous than in normal conditions. In the myocardial areas affected by interstitial fibrosis the lymph capillaries are scanty and subtle. The morphological features, evident in the edematous and the fibrotic regions of the hearts affected by dilated cardiomyopathy, are compared with those induced in the myocardium by damaging the lymph flow experimentally. Our observations suggest a differential response of the lymph system to modified conditions of the tissue and the interstitium.
对扩张型心肌病患者的人体心脏中的毛细淋巴管特征进行了研究。水肿的心肌区域存在扩张的毛细淋巴管，其内皮壁略有凹陷。细胞间粘连并不特别复杂；相邻内皮细胞之间的开放连接比正常情况下更多。在受间质纤维化影响的心肌区域，毛细淋巴管稀少且不明显。将扩张型心肌病患者心脏水肿和纤维化区域中明显的形态学特征与通过实验性破坏淋巴流动在心肌中诱导的特征进行比较。我们的观察结果表明淋巴系统对组织和间质改变的条件有不同的反应。
