Zhang Guilong, Zhang Leixiao, Deng Yanli, Shen Yuquan, Wang Xinling, Yu Yang
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine.
Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine.
Medicine (Baltimore). 2020 Apr;99(14):e19722. doi: 10.1097/MD.0000000000019722.
Chronic low back pain (CLBP) is a clinically common and recurrent disease. However, many trials have shown that auriculotherapy (AT) can effectively treat CLBP. There are currently no systematic reviews of this therapy. The plan aims to evaluate the effectiveness and safety of this treatment in patients with CLBP.
This systematic evaluation will entail an electronic and manual search of all AT for CLBP from inception to January 31, 2020, regardless of the publication status or language. Databases include PubMed, Excerpt Medica Database, Springer, Web of Science, the Cochrane Library, the World Health Organization International Clinical Trial Registration Platform, the Chinese Medicine Database, the China National Knowledge Infrastructure, the Chinese Biomedical Literature Database, the China Science Journal Database, and the Wanfang Database. Other sources of information, including bibliographies and meeting minutes for identified publications, will also be searched. A manual search for grey literature, including unpublished conference articles will be performed. Additionally, any clinical randomized controlled trials related to AT for CLBP, regardless of the publication status and language limitations, will be included in the study. Study selection, data extraction, and research quality assessments will be conducted independently by 2 researchers. The main result was the use of a visual analog scale, a short pain scale, or other effective scale. Secondary outcomes included effectiveness, Oswestry dysfunction index, self-rating anxiety scale, self-depression rating scale, Pittsburgh sleep quality index, follow-up relapse rate, and adverse events. The system searches for randomized controlled trials of this therapy for CLBP. Implement the Cochrane RevMan V5.3 bias assessment tool to assess bias risk, data integration risk, meta-analysis risk, and subgroup analysis risk (if conditions are met). Mean difference, standard mean deviation, and binary data will be used to represent continuous results.
This study will provide a comprehensive review and evaluation of the available evidence for the treatment of CLBP using this therapy.
This study will provide new evidence to evaluate the effectiveness and side effects of AT on CLBP. Because the data is not personalized, no formal ethical approval is required.
CRD42020151584.
慢性下腰痛（CLBP）是一种临床常见的复发性疾病。然而，许多试验表明耳穴疗法（AT）能有效治疗CLBP。目前尚无对该疗法的系统评价。本计划旨在评估该疗法对CLBP患者的有效性和安全性。
本系统评价将对从开始到2020年1月31日所有关于CLBP的耳穴疗法进行电子和手动检索，无论其发表状态或语言如何。数据库包括PubMed、医学文摘数据库、施普林格、科学网、考克兰图书馆、世界卫生组织国际临床试验注册平台、中医药数据库、中国知网、中国生物医学文献数据库、中国科学期刊数据库和万方数据库。还将检索其他信息来源，包括已识别出版物的参考文献和会议记录。将对灰色文献进行手动检索，包括未发表的会议文章。此外，任何与CLBP耳穴疗法相关的临床随机对照试验，无论其发表状态和语言限制如何，都将纳入研究。研究选择、数据提取和研究质量评估将由2名研究人员独立进行。主要结果是使用视觉模拟量表、简短疼痛量表或其他有效量表。次要结果包括有效性、Oswestry功能障碍指数、自评焦虑量表、自评抑郁量表、匹兹堡睡眠质量指数、随访复发率和不良事件。系统检索该疗法治疗CLBP的随机对照试验。使用考克兰RevMan V5.3偏倚评估工具评估偏倚风险、数据整合风险、荟萃分析风险和亚组分析风险（如条件满足）。均值差、标准化均值差和二分类数据将用于表示连续结果。
本研究将对使用该疗法治疗CLBP的现有证据进行全面综述和评价。
本研究将为评估耳穴疗法对CLBP的有效性和副作用提供新证据。由于数据不涉及个人化，无需正式伦理批准。
PROSPERO注册号：CRD42020151584。
